Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CTSL | P07711 | 1/20 | 0.53 |
| ▸ | CTSB | P07858 | 1/20 | 0.53 |
| ▸ | CTSS | P25774 | 1/20 | 0.53 |
| ▸ | CTSK | P43235 | 1/20 | 0.53 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.39 |
| ▸ | LMNA | P02545 | 1/20 | 0.39 |
| ▸ | MEN1 | O00255 | 1/20 | 0.39 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.39 |
| ▸ | ABL1 | P00519 | 1/20 | 0.38 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.38 |
| ▸ | PTGER1 | P34995 | 1/20 | 0.37 |
| ▸ | SLC2A1 | P11166 | 4/20 | 0.37 |
| ▸ | TACR2 | P21452 | 1/20 | 0.35 |
| ▸ | GPR6 | P46095 | 2/20 | 0.35 |
| ▸ | CNR2 | P34972 | 1/20 | 0.35 |
| ▸ | NPC1 | O15118 | 1/20 | 0.34 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.34 |
| ▸ | TP53 | P04637 | 1/20 | 0.34 |
| ▸ | RAB9A | P51151 | 1/20 | 0.34 |
| ▸ | TRPV4 | Q9HBA0 | 3/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Trifluoroacetic Acid SCHEMBL5592935 | 0.94 | CTSL (0.55) | CTSLCTSBCTSSCTSKPTGER1 | |
| Trifluoroacetic Acid SCHEMBL5592743 | 0.93 | CTSL (0.62) | CTSLCTSBCTSSCTSKNPC1 | |
| Trifluoroacetic Acid SCHEMBL5593218 | 0.93 | CTSL (0.56) | CTSLCTSBCTSSCTSKPTGER1 | |
| Trifluoroacetic Acid SCHEMBL5592808 | 0.91 | CTSL (0.56) | CTSLCTSBCTSSCTSKSLC2A1 | |
| SCHEMBL8244881 | 0.91 | CTSL (0.58) | CTSLCTSBCTSSCTSKSMN1; SMN2 | |
| Trifluoroacetic Acid SCHEMBL5592876 | 0.90 | CTSL (0.55) | CTSLCTSBCTSSCTSKPTGER1 | |
| Trifluoroacetic Acid SCHEMBL5593236 | 0.90 | CTSL (0.49) | CTSLCTSBCTSSCTSKSMN1; SMN2 | |
| Trifluoroacetic Acid SCHEMBL5593235 | 0.89 | CTSL (0.55) | CTSLCTSBCTSSCTSKPTGER1 | |
| SCHEMBL5592751 | 0.89 | CTSL (0.59) | CTSLCTSBCTSSCTSKSMN1; SMN2 | |
| SCHEMBL5592666 | 0.88 | CTSL (0.61) | CTSLCTSBCTSSCTSKSMN1; SMN2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2007025775-A2 | CYSTEINE PROTEASE INHIBITORS | GLAXO GROUP LIMITED (GB) | 2007-03-08 | — | — | WO | claimed |