Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CTSL | P07711 | 1/20 | 0.49 |
| ▸ | CTSB | P07858 | 1/20 | 0.49 |
| ▸ | CTSS | P25774 | 1/20 | 0.49 |
| ▸ | CTSK | P43235 | 1/20 | 0.49 |
| ▸ | ACVR1 | Q04771 | 4/20 | 0.41 |
| ▸ | BMPR1B | O00238 | 1/20 | 0.41 |
| ▸ | BMPR1A | P36894 | 1/20 | 0.41 |
| ▸ | TGFBR1 | P36897 | 1/20 | 0.41 |
| ▸ | ACVRL1 | P37023 | 1/20 | 0.41 |
| ▸ | CXCR3 | P49682 | 5/20 | 0.40 |
| ▸ | ACKR3 | P25106 | 3/20 | 0.38 |
| ▸ | TRPV4 | Q9HBA0 | 1/20 | 0.37 |
| ▸ | LMNA | P02545 | 1/20 | 0.37 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.37 |
| ▸ | MEN1 | O00255 | 1/20 | 0.36 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.36 |
| ▸ | CDK14 | O94921 | 1/20 | 0.36 |
| ▸ | CCNY | Q8ND76 | 1/20 | 0.36 |
| ▸ | SLC2A1 | P11166 | 1/20 | 0.36 |
| ▸ | ABL1 | P00519 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Trifluoroacetic Acid SCHEMBL5308534 | 0.93 | CTSL (0.57) | CTSLCTSBCTSSCTSKACVR1 | |
| Trifluoroacetic Acid SCHEMBL5592810 | 0.90 | CTSL (0.53) | CTSLCTSBCTSSCTSKACKR3 | |
| Trifluoroacetic Acid SCHEMBL5592940 | 0.89 | CTSL (0.48) | CTSLCTSBCTSSCTSKACVR1 | |
| Trifluoroacetic Acid SCHEMBL5592919 | 0.89 | CTSL (0.52) | CTSLCTSBCTSSCTSKACKR3 | |
| SCHEMBL5593202 | 0.89 | CTSL (0.54) | CTSLCTSBCTSSCTSKCXCR3 | |
| Trifluoroacetic Acid SCHEMBL5592876 | 0.89 | CTSL (0.55) | CTSLCTSBCTSSCTSKACKR3 | |
| SCHEMBL8244881 | 0.89 | CTSL (0.58) | CTSLCTSBCTSSCTSKACKR3 | |
| SCHEMBL8236804 | 0.88 | CTSS (0.61) | CTSLCTSBCTSSCTSKCXCR3 | |
| Trifluoroacetic Acid SCHEMBL5593235 | 0.88 | CTSL (0.55) | CTSLCTSBCTSSCTSKACKR3 | |
| SCHEMBL5592623 | 0.88 | CTSL (0.62) | CTSLCTSBCTSSCTSKACVR1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2007025775-A2 | CYSTEINE PROTEASE INHIBITORS | GLAXO GROUP LIMITED (GB) | 2007-03-08 | — | — | WO | claimed |