Trifluoroacetic Acid

Trifluoroacetic Acid

SCHEMBL5592919

CC(C)CN(NC(=O)c1cccc(CN2CCC(CO)CC2)c1)c1nc(C#N)ncc1Cl.O=C(O)C(F)(F)F

nearest known ligand 0.52

Full drug profile on Sugi Atlas →

Predicted protein targets (top 15)

geneUniProtsupporting neighboursconfidence
CTSL P07711 1/20 0.52
CTSB P07858 1/20 0.52
CTSS P25774 1/20 0.52
CTSK P43235 1/20 0.52
ACKR3 P25106 5/20 0.39
CHRM4 P08173 4/20 0.39
SLC2A1 P11166 1/20 0.38
CHRM2 P08172 1/20 0.38
CHRM1 P11229 1/20 0.38
KMT2A Q03164 1/20 0.37
CDK14 O94921 1/20 0.36
CCNY Q8ND76 1/20 0.36
GPR6 P46095 1/20 0.36
KCNH2 Q12809 1/20 0.36
CACNA1I Q9P0X4 1/20 0.36

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL5592721 0.95 CTSL (0.56) CTSLCTSBCTSSCTSKACKR3
Trifluoroacetic Acid SCHEMBL5592868 0.93 CTSL (0.60) CTSLCTSBCTSSCTSKACKR3
Trifluoroacetic Acid SCHEMBL5592876 0.92 CTSL (0.55) CTSLCTSBCTSSCTSKACKR3
Trifluoroacetic Acid SCHEMBL5593235 0.91 CTSL (0.55) CTSLCTSBCTSSCTSKACKR3
Trifluoroacetic Acid SCHEMBL5592668 0.91 CTSL (0.58) CTSLCTSBCTSSCTSKACKR3
Trifluoroacetic Acid SCHEMBL5592941 0.91 CTSL (0.51) CTSLCTSBCTSSCTSKACKR3
SCHEMBL5592921 0.90 CTSL (0.51) CTSLCTSBCTSSCTSKACKR3
Trifluoroacetic Acid SCHEMBL5593218 0.89 CTSL (0.56) CTSLCTSBCTSSCTSKACKR3
Trifluoroacetic Acid SCHEMBL5592808 0.89 CTSL (0.56) CTSLCTSBCTSSCTSKACKR3
Trifluoroacetic Acid SCHEMBL5593236 0.89 CTSL (0.49) CTSLCTSBCTSSCTSKACKR3

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
WO-2007025775-A2 CYSTEINE PROTEASE INHIBITORS GLAXO GROUP LIMITED (GB) 2007-03-08 WO claimed