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Trifluoroacetic Acid

Trifluoroacetic Acid

SCHEMBL5592933

CCCN1CCN(Cc2cc(C(=O)NN(CC(C)C)c3nc(C#N)ncc3Cl)ccc2F)CC1.O=C(O)C(F)(F)F

nearest known ligand 0.56

Full drug profile on Sugi Atlas →

Predicted protein targets (top 8)

geneUniProtsupporting neighboursconfidence
▸ CTSL P07711 1/20 0.56
▸ CTSB P07858 1/20 0.56
▸ CTSS P25774 1/20 0.56
▸ CTSK P43235 1/20 0.56
▸ GPR6 P46095 16/20 0.40
▸ SLC2A1 P11166 1/20 0.34
▸ EGFR P00533 1/20 0.33
▸ DDR1 Q08345 1/20 0.33

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
Trifluoroacetic Acid SCHEMBL5592745 0.94 CTSL (0.63) CTSLCTSBCTSSCTSKGPR6
SCHEMBL8245197 0.90 CTSL (0.68) CTSLCTSBCTSSCTSKGPR6
Trifluoroacetic Acid SCHEMBL5592808 0.88 CTSL (0.56) CTSLCTSBCTSSCTSKGPR6
SCHEMBL5592877 0.88 CTSL (0.69) CTSLCTSBCTSSCTSKGPR6
Trifluoroacetic Acid SCHEMBL5592940 0.86 CTSL (0.48) CTSLCTSBCTSSCTSKGPR6
SCHEMBL8243445 0.86 CTSL (0.55) CTSLCTSBCTSSCTSKGPR6
SCHEMBL5592558 0.85 CTSL (0.73) CTSLCTSBCTSSCTSKEGFR
SCHEMBL5592923 0.85 CTSL (0.55) CTSLCTSBCTSSCTSKGPR6
Trifluoroacetic Acid SCHEMBL5592881 0.85 CTSL (0.66) CTSLCTSBCTSSCTSKGPR6
Trifluoroacetic Acid SCHEMBL5592848 0.84 CTSL (0.79) CTSLCTSBCTSSCTSKGPR6

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
WO-2007025775-A2 CYSTEINE PROTEASE INHIBITORS GLAXO GROUP LIMITED (GB) 2007-03-08 — — WO claimed