Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CTSL | P07711 | 1/20 | 0.48 |
| ▸ | CTSB | P07858 | 1/20 | 0.48 |
| ▸ | CTSS | P25774 | 1/20 | 0.48 |
| ▸ | CTSK | P43235 | 1/20 | 0.48 |
| ▸ | GPR6 | P46095 | 6/20 | 0.36 |
| ▸ | JAK2 | O60674 | 2/20 | 0.36 |
| ▸ | JAK1 | P23458 | 2/20 | 0.36 |
| ▸ | JAK3 | P52333 | 2/20 | 0.36 |
| ▸ | DDR1 | Q08345 | 3/20 | 0.36 |
| ▸ | ACVR1 | Q04771 | 3/20 | 0.35 |
| ▸ | BMPR1B | O00238 | 1/20 | 0.35 |
| ▸ | BMPR1A | P36894 | 1/20 | 0.35 |
| ▸ | TGFBR1 | P36897 | 1/20 | 0.35 |
| ▸ | ACVRL1 | P37023 | 1/20 | 0.35 |
| ▸ | CXCR3 | P49682 | 3/20 | 0.35 |
| ▸ | TRPV4 | Q9HBA0 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5592747 | 0.96 | CTSL (0.52) | CTSLCTSBCTSSCTSKJAK2 | |
| Trifluoroacetic Acid SCHEMBL5308534 | 0.91 | CTSL (0.57) | CTSLCTSBCTSSCTSKJAK2 | |
| Trifluoroacetic Acid SCHEMBL5593236 | 0.89 | CTSL (0.49) | CTSLCTSBCTSSCTSKACVR1 | |
| Trifluoroacetic Acid SCHEMBL5592745 | 0.88 | CTSL (0.63) | CTSLCTSBCTSSCTSKGPR6 | |
| Trifluoroacetic Acid SCHEMBL5592933 | 0.86 | CTSL (0.56) | CTSLCTSBCTSSCTSKGPR6 | |
| SCHEMBL5592623 | 0.86 | CTSL (0.62) | CTSLCTSBCTSSCTSKJAK2 | |
| SCHEMBL5592923 | 0.85 | CTSL (0.55) | CTSLCTSBCTSSCTSKGPR6 | |
| SCHEMBL8243445 | 0.85 | CTSL (0.55) | CTSLCTSBCTSSCTSKGPR6 | |
| SCHEMBL8245197 | 0.83 | CTSL (0.68) | CTSLCTSBCTSSCTSKGPR6 | |
| Trifluoroacetic Acid SCHEMBL5591222 | 0.83 | CTSL (0.43) | CTSLCTSBCTSSCTSKGPR6 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2007025775-A2 | CYSTEINE PROTEASE INHIBITORS | GLAXO GROUP LIMITED (GB) | 2007-03-08 | — | — | WO | claimed |