Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CTSL | P07711 | 3/20 | 0.79 |
| ▸ | CTSS | P25774 | 3/20 | 0.79 |
| ▸ | CTSK | P43235 | 3/20 | 0.79 |
| ▸ | CTSB | P07858 | 2/20 | 0.79 |
| ▸ | TBK1 | Q9UHD2 | 5/20 | 0.35 |
| ▸ | IKBKE | Q14164 | 4/20 | 0.35 |
| ▸ | HDAC6 | Q9UBN7 | 1/20 | 0.35 |
| ▸ | HDAC4 | P56524 | 2/20 | 0.34 |
| ▸ | HDAC1 | Q13547 | 2/20 | 0.34 |
| ▸ | HIF1A | Q16665 | 3/20 | 0.34 |
| ▸ | EPAS1 | Q99814 | 3/20 | 0.34 |
| ▸ | GPR6 | P46095 | 2/20 | 0.34 |
| ▸ | CSF1R | P07333 | 1/20 | 0.34 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.33 |
| ▸ | SLC2A1 | P11166 | 1/20 | 0.33 |
| ▸ | JAK2 | O60674 | 1/20 | 0.33 |
| ▸ | JAK3 | P52333 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5592822 | 0.95 | CTSS (0.88) | CTSLCTSSCTSKCTSBTBK1 | |
| Trifluoroacetic Acid SCHEMBL3319243 | 0.94 | CTSS (0.90) | CTSLCTSSCTSKCTSBTBK1 | |
| Trifluoroacetic Acid SCHEMBL5592621 | 0.92 | CTSL (0.78) | CTSLCTSSCTSKCTSBHDAC6 | |
| Trifluoroacetic Acid SCHEMBL5592904 | 0.92 | CTSL (0.66) | CTSLCTSSCTSKCTSBHDAC1 | |
| SCHEMBL5592896 | 0.89 | CTSS (1.00) | CTSLCTSSCTSKCTSBTBK1 | |
| Trifluoroacetic Acid SCHEMBL5591489 | 0.88 | CTSS (0.61) | CTSLCTSSCTSKCTSBHDAC6 | |
| SCHEMBL5593246 | 0.87 | CTSL (0.87) | CTSLCTSSCTSKCTSBTBK1 | |
| SCHEMBL5592618 | 0.87 | CTSL (0.87) | CTSLCTSSCTSKCTSBTBK1 | |
| SCHEMBL5592558 | 0.86 | CTSL (0.73) | CTSLCTSSCTSKCTSBTBK1 | |
| SCHEMBL5593209 | 0.86 | CTSL (0.86) | CTSLCTSSCTSKCTSBTBK1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2007025775-A2 | CYSTEINE PROTEASE INHIBITORS | GLAXO GROUP LIMITED (GB) | 2007-03-08 | — | — | WO | claimed |