Predicted protein targets (top 9)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LMNA | P02545 | 1/20 | 0.34 |
| ▸ | ADORA2A | P29274 | 2/20 | 0.33 |
| ▸ | ADORA1 | P30542 | 2/20 | 0.33 |
| ▸ | GAA | P10253 | 1/20 | 0.32 |
| ▸ | TSHR | P16473 | 1/20 | 0.32 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.32 |
| ▸ | PPARG | P37231 | 3/20 | 0.32 |
| ▸ | PPARA | Q07869 | 3/20 | 0.32 |
| ▸ | ADORA2B | P29275 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4639469 | 0.93 | LMNA (0.35) | LMNAADORA2AADORA1GAATSHR | |
| SCHEMBL4639667 | 0.90 | S1PR1 (0.37) | LMNA | |
| SCHEMBL5593005 | 0.90 | S1PR1 (0.34) | LMNAADORA2AADORA1PPARGPPARA | |
| SCHEMBL4639774 | 0.89 | MGAM (0.38) | ADORA2AADORA1GAAKMT2A | |
| SCHEMBL4640553 | 0.88 | FPR2 (0.34) | — | |
| SCHEMBL4639491 | 0.87 | PDE4D (0.34) | LMNAADORA2AADORA1 | |
| SCHEMBL4641206 | 0.87 | PARP1 (0.31) | LMNAADORA2AADORA1 | |
| SCHEMBL4639663 | 0.85 | ADORA2A (0.30) | LMNAADORA2AADORA1 | |
| SCHEMBL4639593 | 0.85 | LCLAT1 (0.34) | LMNAGAATSHRKMT2A | |
| SCHEMBL4639813 | 0.82 | S1PR1 (0.43) | LMNAKMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2007058338-A9 | OXAZOLE COMPOUND AND PHARMACEUTICAL COMPOSITION | OTSUKA PHARMA CO LTD (JP) | 2007-11-01 | — | — | WO | disclosed |