Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | S1PR1 | P21453 | 5/20 | 0.34 |
| ▸ | S1PR3 | Q99500 | 3/20 | 0.34 |
| ▸ | S1PR5 | Q9H228 | 3/20 | 0.34 |
| ▸ | LMNA | P02545 | 1/20 | 0.33 |
| ▸ | PPARG | P37231 | 3/20 | 0.33 |
| ▸ | PPARA | Q07869 | 3/20 | 0.33 |
| ▸ | ADORA2A | P29274 | 1/20 | 0.32 |
| ▸ | ADORA1 | P30542 | 1/20 | 0.32 |
| ▸ | PDE4D | Q08499 | 2/20 | 0.32 |
| ▸ | SYK | P43405 | 1/20 | 0.32 |
| ▸ | PDE4A | P27815 | 1/20 | 0.32 |
| ▸ | PDE4B | Q07343 | 1/20 | 0.32 |
| ▸ | PDE4C | Q08493 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4639469 | 0.96 | LMNA (0.35) | S1PR1LMNAPPARGPPARAADORA2A | |
| SCHEMBL4639667 | 0.91 | S1PR1 (0.37) | S1PR1S1PR3LMNA | |
| SCHEMBL4640553 | 0.90 | FPR2 (0.34) | PDE4DPDE4APDE4BPDE4C | |
| SCHEMBL5592943 | 0.90 | LMNA (0.34) | LMNAPPARGPPARAADORA2AADORA1 | |
| SCHEMBL4639491 | 0.88 | PDE4D (0.34) | S1PR1LMNAADORA2AADORA1PDE4D | |
| SCHEMBL4641206 | 0.88 | PARP1 (0.31) | LMNAADORA2AADORA1PDE4D | |
| SCHEMBL4639663 | 0.87 | ADORA2A (0.30) | LMNAADORA2AADORA1 | |
| SCHEMBL4639813 | 0.83 | S1PR1 (0.43) | S1PR1S1PR3LMNA | |
| SCHEMBL4277707 | 0.82 | S1PR1 (0.37) | S1PR1S1PR3S1PR5PPARGPPARA | |
| SCHEMBL4271374 | 0.82 | S1PR1 (0.37) | S1PR1S1PR3S1PR5PPARGPPARA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2007058338-A9 | OXAZOLE COMPOUND AND PHARMACEUTICAL COMPOSITION | OTSUKA PHARMA CO LTD (JP) | 2007-11-01 | — | — | WO | disclosed |