Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | RAB9A | P51151 | 4/20 | 0.48 |
| ▸ | NPC1 | O15118 | 3/20 | 0.48 |
| ▸ | LMNA | P02545 | 1/20 | 0.47 |
| ▸ | HPGD | P15428 | 5/20 | 0.46 |
| ▸ | POLB | P06746 | 5/20 | 0.46 |
| ▸ | MEN1 | O00255 | 2/20 | 0.46 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.46 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.46 |
| ▸ | HDAC8 | Q9BY41 | 1/20 | 0.46 |
| ▸ | HDAC6 | Q9UBN7 | 1/20 | 0.46 |
| ▸ | HDAC1 | Q13547 | 3/20 | 0.45 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.43 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.43 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.43 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.43 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.43 |
| ▸ | CA1 | P00915 | 1/20 | 0.43 |
| ▸ | CA2 | P00918 | 1/20 | 0.43 |
| ▸ | CA5A | P35218 | 1/20 | 0.43 |
| ▸ | CA7 | P43166 | 1/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3615851 | 0.88 | LMNA (0.51) | RAB9ANPC1LMNAHPGDPOLB | |
| SCHEMBL8250477 | 0.87 | RAB9A (0.51) | RAB9ANPC1LMNAHPGDPOLB | |
| SCHEMBL5593007 | 0.87 | RAB9A (0.48) | RAB9ANPC1LMNAHPGDPOLB | |
| SCHEMBL8248244 | 0.86 | HDAC6 (0.64) | RAB9ANPC1LMNAHPGDHDAC8 | |
| SCHEMBL13316890 | 0.85 | HDAC6 (0.50) | RAB9ANPC1LMNAHPGDPOLB | |
| SCHEMBL8249116 | 0.83 | HDAC1 (0.47) | RAB9ANPC1HPGDPOLBMEN1 | |
| SCHEMBL8249138 | 0.83 | RAB9A (0.48) | RAB9ANPC1LMNAHPGDPOLB | |
| SCHEMBL8246236 | 0.83 | RAB9A (0.51) | RAB9ANPC1HPGDPOLBMEN1 | |
| SCHEMBL8250856 | 0.83 | RAB9A (0.47) | RAB9ANPC1LMNAHPGDPOLB | |
| SCHEMBL8239129 | 0.83 | PLAU (0.46) | RAB9ANPC1LMNAHPGDPOLB |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2007017728-A2 | NOVEL HETEROCYCLIC COMPOUNDS | ORCHID RESEARCH LABORATORIES LIMITED (IN) | 2007-02-15 | — | — | WO | claimed |