Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | RAB9A | P51151 | 5/20 | 0.51 |
| ▸ | NPC1 | O15118 | 5/20 | 0.51 |
| ▸ | POLB | P06746 | 5/20 | 0.49 |
| ▸ | HPGD | P15428 | 5/20 | 0.49 |
| ▸ | MEN1 | O00255 | 2/20 | 0.49 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.49 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.49 |
| ▸ | BLM | P54132 | 1/20 | 0.49 |
| ▸ | LMNA | P02545 | 1/20 | 0.47 |
| ▸ | HDAC8 | Q9BY41 | 1/20 | 0.46 |
| ▸ | HDAC6 | Q9UBN7 | 1/20 | 0.46 |
| ▸ | HDAC1 | Q13547 | 2/20 | 0.45 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.44 |
| ▸ | HDAC2 | Q92769 | 1/20 | 0.44 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3615851 | 0.88 | LMNA (0.51) | RAB9ANPC1POLBHPGDMEN1 | |
| SCHEMBL13316890 | 0.88 | HDAC6 (0.50) | RAB9ANPC1POLBHPGDSMN1; SMN2 | |
| SCHEMBL5593004 | 0.87 | RAB9A (0.48) | RAB9ANPC1POLBHPGDMEN1 | |
| SCHEMBL5593007 | 0.87 | RAB9A (0.48) | RAB9ANPC1POLBHPGDMEN1 | |
| SCHEMBL8248244 | 0.86 | HDAC6 (0.64) | RAB9ANPC1HPGDLMNAHDAC8 | |
| SCHEMBL8249116 | 0.86 | HDAC1 (0.47) | RAB9ANPC1POLBHPGDMEN1 | |
| SCHEMBL8250856 | 0.85 | RAB9A (0.47) | RAB9ANPC1POLBHPGDMEN1 | |
| SCHEMBL8246236 | 0.85 | RAB9A (0.51) | RAB9ANPC1POLBHPGDMEN1 | |
| SCHEMBL29627349 | 0.85 | RAB9A (0.69) | RAB9ANPC1POLBHPGDMEN1 | |
| SCHEMBL8250405 | 0.83 | RAB9A (0.46) | RAB9ANPC1POLBHPGDMEN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2007017728-A2 | NOVEL HETEROCYCLIC COMPOUNDS | ORCHID RESEARCH LABORATORIES LIMITED (IN) | 2007-02-15 | — | — | WO | disclosed |