Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ACHE | P22303 | 4/20 | 0.68 |
| ▸ | BCHE | P06276 | 3/20 | 0.68 |
| ▸ | TSHR | P16473 | 1/20 | 0.49 |
| ▸ | GFER | P55789 | 1/20 | 0.49 |
| ▸ | KDM4E | B2RXH2 | 4/20 | 0.47 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.47 |
| ▸ | HRH3 | Q9Y5N1 | 1/20 | 0.47 |
| ▸ | MPO | P05164 | 2/20 | 0.46 |
| ▸ | CACNA1B | Q00975 | 1/20 | 0.45 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.45 |
| ▸ | HTT | P42858 | 1/20 | 0.45 |
| ▸ | MAOB | P27338 | 1/20 | 0.44 |
| ▸ | BRD4 | O60885 | 1/20 | 0.43 |
| ▸ | LMNA | P02545 | 1/20 | 0.43 |
| ▸ | TP53 | P04637 | 1/20 | 0.43 |
| ▸ | GAA | P10253 | 1/20 | 0.43 |
| ▸ | MAPT | P10636 | 1/20 | 0.43 |
| ▸ | ALOX12 | P18054 | 1/20 | 0.43 |
| ▸ | NFKB1 | P19838 | 1/20 | 0.43 |
| ▸ | NFKB2 | Q00653 | 1/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL20210279 | 0.85 | KDM4E (0.63) | ACHEBCHETSHRGFERKDM4E | |
| SCHEMBL13306136 | 0.80 | ACHE (0.57) | ACHEBCHETSHRGFERKDM4E | |
| SCHEMBL9685461 | 0.78 | PRMT6 (0.56) | ACHEBCHEKDM4ESMN1; SMN2HRH3 | |
| SCHEMBL2012519 | 0.77 | ACHE (0.75) | ACHEBCHETSHRGFERKDM4E | |
| SCHEMBL14423575 | 0.77 | ACHE (0.54) | ACHEBCHETSHRGFERKDM4E | |
| SCHEMBL29938949 | 0.77 | ACHE (0.75) | ACHEBCHETSHRGFERKDM4E | |
| SCHEMBL29021851 | 0.77 | ACHE (0.63) | ACHEBCHETSHRGFERKDM4E | |
| SCHEMBL14424032 | 0.76 | ACHE (0.53) | ACHEBCHETSHRGFERALDH1A1 | |
| SCHEMBL2511328 | 0.76 | MAOB (0.59) | ACHEBCHETSHRGFERKDM4E | |
| SCHEMBL13339098 | 0.76 | MAOB (0.59) | ACHEBCHETSHRGFERKDM4E |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2007104695-A1 | QUINOLIN-4-YLHYDRAZINE DERIVATIVES AS ANTIMALARIAL AGENT | SIGMA-TAU INDUSTRIE FARMACEUTICHE RIUNITE S.P.A. (IT) | 2007-09-20 | — | — | WO | disclosed |
| WO-2007104695-A1 | QUINOLIN-4-YLHYDRAZINE DERIVATIVES AS ANTIMALARIAL AGENT | SIGMA-TAU INDUSTRIE FARMACEUTICHE RIUNITE S.P.A. (IT) | 2007-09-20 | — | — | WO | disclosed |