Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PRMT6 | Q96LA8 | 1/20 | 0.56 |
| ▸ | ACHE | P22303 | 4/20 | 0.55 |
| ▸ | BCHE | P06276 | 3/20 | 0.55 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.51 |
| ▸ | HTT | P42858 | 1/20 | 0.51 |
| ▸ | HRH3 | Q9Y5N1 | 2/20 | 0.50 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.47 |
| ▸ | POLB | P06746 | 1/20 | 0.47 |
| ▸ | HRH4 | Q9H3N8 | 1/20 | 0.46 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.45 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.45 |
| ▸ | HIF1A | Q16665 | 1/20 | 0.45 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.44 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7379184 | 0.80 | HRH3 (0.59) | PRMT6ACHEALDH1A1HTTHRH3 | |
| SCHEMBL1934369 | 0.80 | ALDH1A1 (0.65) | PRMT6ALDH1A1HTTHRH3SMN1; SMN2 | |
| SCHEMBL23692383 | 0.79 | ALDH1A1 (0.69) | PRMT6ACHEBCHEALDH1A1HTT | |
| SCHEMBL31260442 | 0.79 | HRH3 (0.53) | PRMT6ACHEBCHEALDH1A1HTT | |
| SCHEMBL5593151 | 0.78 | ACHE (0.68) | ACHEBCHEALDH1A1HTTHRH3 | |
| SCHEMBL5722022 | 0.78 | ALDH1A1 (0.58) | PRMT6ACHEBCHEALDH1A1HTT | |
| SCHEMBL30334815 | 0.78 | ALDH1A1 (0.72) | ACHEBCHEALDH1A1HTTHRH3 | |
| SCHEMBL10061486 | 0.78 | PRMT6 (0.57) | PRMT6ACHEALDH1A1HTTHRH3 | |
| SCHEMBL20238021 | 0.77 | ALDH1A1 (0.60) | PRMT6ALDH1A1HTTHRH3SMN1; SMN2 | |
| SCHEMBL30334972 | 0.76 | ALDH1A1 (0.64) | ACHEBCHEALDH1A1HTTHRH3 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0288519-A4 | 1-TERTIARY-ALKYL-SUBSTITUTED NAPHTHYRIDINE- AND QUINOLINE-CARBOXYLIC ACID ANTIBACTERIAL AGENTS | — | 1992-04-15 | — | — | EP | disclosed |
| US-4965273-A | Certain 1-tertiary-butyl-naphthyridone carboxylic acid derivatives anti-bacterial agents | BRISTOL-MYERS COMPANY (US) | 1990-10-23 | — | — | US | disclosed |
| US-4954507-A | 1-tertiary-alkyl-substituted naphthyridine carboxylic acid antibacterial agents | BRISTOL-MYERS COMPANY (US) | 1990-09-04 | — | — | US | disclosed |
| EP-0288519-A1 | 1-TERTIARY-ALKYL-SUBSTITUTED NAPHTHYRIDINE- AND QUINOLINE-CARBOXYLIC ACID ANTIBACTERIAL AGENTS | Bristol-Myers Squibb Company (US) | 1988-11-02 | — | — | EP | disclosed |
| EP-0266576-A2 | 1-Tert-alkyl-substituted naphthyridine and quinoline carboxylic acids as antibacterial agents | Bristol-Myers Squibb Company (US) | 1988-05-11 | — | — | EP | disclosed |
| WO-1988002627-A1 | 1-TERTIARY-ALKYL-SUBSTITUTED NAPHTHYRIDINE- AND QUINOLINE-CARBOXYLIC ACID ANTIBACTERIAL AGENTS | BRISTOL-MYERS COMPANY (US) | 1988-04-21 | — | — | WO | disclosed |