SCHEMBL5593201

SCHEMBL5593201

Cc1cc(F)c(-c2c(C)nc3ncnn3c2N2CCC(C)C2)cc1F

nearest known ligand 0.41

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
EGLN2 Q96KS0 1/20 0.41
LMNA P02545 6/20 0.40
ALDH1A1 P00352 4/20 0.40
PAX2 Q02962 1/20 0.39
TSHR P16473 4/20 0.39
NPSR1 Q6W5P4 2/20 0.39
GLA P06280 1/20 0.39
SMN1; SMN2 Q16637 5/20 0.38
MAPT P10636 3/20 0.38
PDE2A O00408 4/20 0.37
HTT P42858 3/20 0.36
MEN1 O00255 1/20 0.36
KMT2A Q03164 1/20 0.36
GAA P10253 2/20 0.35
MAPK1 P28482 2/20 0.35
ALOX15 P16050 1/20 0.35
L3MBTL1 Q9Y468 1/20 0.35
KDM4E B2RXH2 1/20 0.35
USP2 O75604 1/20 0.35
HPGD P15428 1/20 0.35

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL5593344 0.95 LMNA (0.44) EGLN2LMNAALDH1A1PAX2TSHR
SCHEMBL5593160 0.94 LMNA (0.43) LMNAALDH1A1PAX2TSHRNPSR1
SCHEMBL5593438 0.90 EGLN2 (0.39) EGLN2LMNAALDH1A1PAX2TSHR
SCHEMBL5593377 0.88 EGLN2 (0.38) EGLN2LMNAALDH1A1TSHRNPSR1
SCHEMBL5593398 0.88 PDE2A (0.42) EGLN2LMNAALDH1A1PAX2TSHR
SCHEMBL5593085 0.88 EGLN2 (0.46) EGLN2LMNAALDH1A1TSHRNPSR1
SCHEMBL5593192 0.85 PAX2 (0.43) EGLN2LMNAALDH1A1PAX2TSHR
SCHEMBL5593427 0.84 ALDH1A1 (0.41) EGLN2LMNAALDH1A1PAX2TSHR
SCHEMBL5593136 0.84 PDE2A (0.39) LMNATSHRNPSR1GLAPDE2A
SCHEMBL5593364 0.83 LMNA (0.42) LMNAALDH1A1PAX2TSHRNPSR1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
WO-2007099092-A1 SUBSTITUTED 6-PHENYL-7-AMINO[1,2,4]-TRIAZOLO[1,5-a]PYRIMIDINES AND THEIR USE FOR CONTROLLING PATHOGENIC FUNGI BASF SE (DE) 2007-09-07 WO claimed
WO-2007099092-A1 SUBSTITUTED 6-PHENYL-7-AMINO[1,2,4]-TRIAZOLO[1,5-a]PYRIMIDINES AND THEIR USE FOR CONTROLLING PATHOGENIC FUNGI BASF SE (DE) 2007-09-07 WO disclosed