Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NPC1 | O15118 | 2/20 | 0.43 |
| ▸ | RAB9A | P51151 | 2/20 | 0.43 |
| ▸ | HTT | P42858 | 3/20 | 0.36 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.36 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.35 |
| ▸ | MAPT | P10636 | 4/20 | 0.34 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.34 |
| ▸ | GAA | P10253 | 2/20 | 0.34 |
| ▸ | LMNA | P02545 | 1/20 | 0.34 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.34 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.34 |
| ▸ | MEN1 | O00255 | 1/20 | 0.34 |
| ▸ | THRB | P10828 | 1/20 | 0.34 |
| ▸ | TAS2R8 | Q9NYW2 | 1/20 | 0.34 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.34 |
| ▸ | POLB | P06746 | 1/20 | 0.34 |
| ▸ | RECQL | P46063 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4410261 | 0.95 | NPC1 (0.39) | NPC1RAB9AMAPTALDH1A1LMNA | |
| SCHEMBL4409883 | 0.90 | MAPK14 (0.36) | SMN1; SMN2MAPTALDH1A1KDM4E | |
| SCHEMBL4413425 | 0.89 | GAA (0.39) | RAB9ASMN1; SMN2KMT2AMAPTALDH1A1 | |
| SCHEMBL4411278 | 0.89 | MAPT (0.37) | NPC1RAB9AMAPTALDH1A1GAA | |
| SCHEMBL4412714 | 0.88 | MAPT (0.35) | SMN1; SMN2MAPTGAALMNATHRB | |
| SCHEMBL4411132 | 0.81 | BRAF (0.38) | KMT2AMAPTMEN1THRB | |
| SCHEMBL4410028 | 0.80 | MAPT (0.38) | SMN1; SMN2MAPTTHRBKDM4E | |
| SCHEMBL4565792 | 0.80 | MAPT (0.41) | NPC1RAB9AKMT2AMAPTALDH1A1 | |
| SCHEMBL5603582 | 0.79 | MAPK14 (0.37) | SMN1; SMN2MAPTALDH1A1KDM4EPOLB | |
| SCHEMBL4410129 | 0.78 | MEN1 (0.44) | NPC1RAB9AHTTSMN1; SMN2KMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2007075896-A2 | HETEROCYCLIC CYTOKINE INHIBITORS | KEMIA, INC. (US) | 2007-07-05 | — | — | WO | disclosed |