Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TSHR | P16473 | 4/20 | 0.40 |
| ▸ | MAPK1 | P28482 | 3/20 | 0.39 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.39 |
| ▸ | HTT | P42858 | 3/20 | 0.38 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.38 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.37 |
| ▸ | LMNA | P02545 | 1/20 | 0.37 |
| ▸ | ENPP1 | P22413 | 2/20 | 0.36 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.35 |
| ▸ | MEN1 | O00255 | 1/20 | 0.35 |
| ▸ | POLB | P06746 | 1/20 | 0.35 |
| ▸ | EGLN2 | Q96KS0 | 1/20 | 0.35 |
| ▸ | NPC1 | O15118 | 1/20 | 0.35 |
| ▸ | GALR3 | O60755 | 1/20 | 0.35 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.35 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.35 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.35 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5593471 | 0.89 | ALDH1A1 (0.36) | TSHRMAPK1ALOX15HTTSMN1; SMN2 | |
| SCHEMBL5593386 | 0.88 | SMN1; SMN2 (0.35) | TSHRMAPK1ALOX15HTTSMN1; SMN2 | |
| SCHEMBL5593411 | 0.88 | SMN1; SMN2 (0.41) | TSHRHTTSMN1; SMN2ALDH1A1LMNA | |
| SCHEMBL5593361 | 0.87 | EGLN2 (0.40) | TSHRMAPK1ALOX15HTTALDH1A1 | |
| SCHEMBL5593451 | 0.85 | MBOAT4 (0.42) | TSHRMAPK1ALOX15HTTSMN1; SMN2 | |
| SCHEMBL5593434 | 0.84 | MAPK1 (0.40) | TSHRMAPK1ALOX15HTTSMN1; SMN2 | |
| SCHEMBL5593145 | 0.83 | MAPK1 (0.40) | TSHRMAPK1ALOX15HTTSMN1; SMN2 | |
| SCHEMBL5593155 | 0.82 | MAPK1 (0.39) | TSHRMAPK1ALOX15HTTSMN1; SMN2 | |
| SCHEMBL5593490 | 0.82 | MAPK1 (0.39) | TSHRMAPK1ALOX15HTTSMN1; SMN2 | |
| SCHEMBL5593223 | 0.81 | TSHR (0.38) | TSHRMAPK1ALOX15HTTSMN1; SMN2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2007099092-A1 | SUBSTITUTED 6-PHENYL-7-AMINO[1,2,4]-TRIAZOLO[1,5-a]PYRIMIDINES AND THEIR USE FOR CONTROLLING PATHOGENIC FUNGI | BASF SE (DE) | 2007-09-07 | — | — | WO | claimed |
| WO-2007099092-A1 | SUBSTITUTED 6-PHENYL-7-AMINO[1,2,4]-TRIAZOLO[1,5-a]PYRIMIDINES AND THEIR USE FOR CONTROLLING PATHOGENIC FUNGI | BASF SE (DE) | 2007-09-07 | — | — | WO | disclosed |