Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SMN1; SMN2 | Q16637 | 6/20 | 0.35 |
| ▸ | TSHR | P16473 | 5/20 | 0.35 |
| ▸ | HTT | P42858 | 5/20 | 0.35 |
| ▸ | LMNA | P02545 | 4/20 | 0.35 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.35 |
| ▸ | MAPK1 | P28482 | 3/20 | 0.35 |
| ▸ | GALR3 | O60755 | 2/20 | 0.35 |
| ▸ | CYP1A2 | P05177 | 2/20 | 0.35 |
| ▸ | CYP2D6 | P10635 | 2/20 | 0.35 |
| ▸ | CYP2C9 | P11712 | 2/20 | 0.35 |
| ▸ | CYP2C19 | P33261 | 2/20 | 0.35 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.35 |
| ▸ | NPC1 | O15118 | 1/20 | 0.35 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.33 |
| ▸ | RAB9A | P51151 | 1/20 | 0.33 |
| ▸ | EGLN2 | Q96KS0 | 1/20 | 0.33 |
| ▸ | ENPP1 | P22413 | 2/20 | 0.32 |
| ▸ | CRHR1 | P34998 | 1/20 | 0.32 |
| ▸ | HPGD | P15428 | 1/20 | 0.32 |
| ▸ | MEN1 | O00255 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5593367 | 0.90 | SMN1; SMN2 (0.36) | SMN1; SMN2TSHRHTTLMNAALDH1A1 | |
| SCHEMBL5593373 | 0.88 | TSHR (0.40) | SMN1; SMN2TSHRHTTLMNAALDH1A1 | |
| SCHEMBL5593248 | 0.86 | MBOAT4 (0.36) | SMN1; SMN2TSHRHTTLMNAALDH1A1 | |
| SCHEMBL5593471 | 0.86 | ALDH1A1 (0.36) | SMN1; SMN2TSHRHTTLMNAALDH1A1 | |
| SCHEMBL5593494 | 0.85 | CRHR1 (0.37) | SMN1; SMN2TSHRHTTLMNAALDH1A1 | |
| SCHEMBL5593343 | 0.85 | MAPK1 (0.35) | SMN1; SMN2TSHRHTTLMNAALDH1A1 | |
| SCHEMBL5593361 | 0.83 | EGLN2 (0.40) | TSHRHTTALDH1A1MAPK1ALOX15 | |
| SCHEMBL5593399 | 0.83 | MAPK1 (0.34) | SMN1; SMN2TSHRHTTLMNAALDH1A1 | |
| SCHEMBL5593334 | 0.83 | MAPK1 (0.34) | SMN1; SMN2TSHRHTTALDH1A1MAPK1 | |
| SCHEMBL5593079 | 0.83 | SMN1; SMN2 (0.33) | SMN1; SMN2TSHRHTTLMNAALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2007099092-A1 | SUBSTITUTED 6-PHENYL-7-AMINO[1,2,4]-TRIAZOLO[1,5-a]PYRIMIDINES AND THEIR USE FOR CONTROLLING PATHOGENIC FUNGI | BASF SE (DE) | 2007-09-07 | — | — | WO | claimed |
| WO-2007099092-A1 | SUBSTITUTED 6-PHENYL-7-AMINO[1,2,4]-TRIAZOLO[1,5-a]PYRIMIDINES AND THEIR USE FOR CONTROLLING PATHOGENIC FUNGI | BASF SE (DE) | 2007-09-07 | — | — | WO | disclosed |