Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.58 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.58 |
| ▸ | TSHR | P16473 | 3/20 | 0.51 |
| ▸ | SMN1; SMN2 | Q16637 | 4/20 | 0.42 |
| ▸ | MAPT | P10636 | 3/20 | 0.42 |
| ▸ | NPC1 | O15118 | 2/20 | 0.42 |
| ▸ | RAB9A | P51151 | 2/20 | 0.42 |
| ▸ | LMNA | P02545 | 2/20 | 0.42 |
| ▸ | POLB | P06746 | 1/20 | 0.40 |
| ▸ | HPGD | P15428 | 1/20 | 0.40 |
| ▸ | MEN1 | O00255 | 4/20 | 0.39 |
| ▸ | KMT2A | Q03164 | 4/20 | 0.39 |
| ▸ | ALOX12 | P18054 | 1/20 | 0.39 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.39 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.39 |
| ▸ | KAT2B | Q92831 | 1/20 | 0.38 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.38 |
| ▸ | FGF23 | Q9GZV9 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7900527 | 0.81 | GPR35 (0.53) | ALDH1A1TDP1TSHRSMN1; SMN2MAPT | |
| SCHEMBL7900525 | 0.81 | GPR35 (0.53) | ALDH1A1TDP1TSHRSMN1; SMN2MAPT | |
| SCHEMBL16956500 | 0.81 | ALDH1A1 (0.64) | ALDH1A1TDP1TSHRSMN1; SMN2MAPT | |
| SCHEMBL722136 | 0.79 | ALDH1A1 (0.67) | ALDH1A1TDP1TSHRSMN1; SMN2MAPT | |
| SCHEMBL24331538 | 0.78 | ALDH1A1 (0.60) | ALDH1A1TDP1TSHRSMN1; SMN2MAPT | |
| SCHEMBL14332786 | 0.77 | ALDH1A1 (0.64) | ALDH1A1TDP1TSHRSMN1; SMN2MAPT | |
| SCHEMBL4890541 | 0.77 | ALDH1A1 (0.58) | ALDH1A1TDP1TSHRSMN1; SMN2MAPT | |
| SCHEMBL635089 | 0.75 | ALDH1A1 (1.00) | ALDH1A1TDP1TSHRSMN1; SMN2MAPT | |
| SCHEMBL10613251 | 0.74 | MAPT (0.58) | ALDH1A1TDP1TSHRSMN1; SMN2MAPT | |
| SCHEMBL10341377 | 0.74 | MAPT (0.58) | ALDH1A1TDP1TSHRSMN1; SMN2MAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2007075896-A2 | HETEROCYCLIC CYTOKINE INHIBITORS | KEMIA, INC. (US) | 2007-07-05 | — | — | WO | disclosed |