Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | RAB9A | P51151 | 4/20 | 0.54 |
| ▸ | NPC1 | O15118 | 3/20 | 0.54 |
| ▸ | ATM | Q13315 | 1/20 | 0.53 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.51 |
| ▸ | POLB | P06746 | 2/20 | 0.50 |
| ▸ | HPGD | P15428 | 5/20 | 0.49 |
| ▸ | ROCK2 | O75116 | 2/20 | 0.48 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.46 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.46 |
| ▸ | TP53 | P04637 | 1/20 | 0.45 |
| ▸ | TSHR | P16473 | 1/20 | 0.45 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.45 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.45 |
| ▸ | GAA | P10253 | 1/20 | 0.45 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.45 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.45 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5616693 | 0.89 | RAB9A (0.54) | RAB9ANPC1ATMSMN1; SMN2POLB | |
| SCHEMBL5603888 | 0.85 | RAB9A (0.57) | RAB9ANPC1ATMSMN1; SMN2POLB | |
| SCHEMBL14473326 | 0.79 | RAB9A (0.51) | RAB9ANPC1ATMSMN1; SMN2POLB | |
| SCHEMBL4412422 | 0.79 | RAB9A (0.51) | RAB9ANPC1ATMSMN1; SMN2POLB | |
| SCHEMBL5593266 | 0.78 | RAB9A (0.50) | RAB9ANPC1 | |
| SCHEMBL14473018 | 0.78 | RAB9A (0.50) | RAB9ANPC1ATMSMN1; SMN2POLB | |
| SCHEMBL4420730 | 0.78 | RAB9A (0.50) | RAB9ANPC1ATMSMN1; SMN2POLB | |
| SCHEMBL5592981 | 0.77 | RAF1 (0.54) | RAB9ANPC1 | |
| SCHEMBL5593020 | 0.77 | RAB9A (0.49) | RAB9ANPC1ATMSMN1; SMN2HPGD | |
| SCHEMBL5592999 | 0.77 | RAB9A (0.47) | RAB9ANPC1ATMSMN1; SMN2POLB |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2007075896-A2 | HETEROCYCLIC CYTOKINE INHIBITORS | KEMIA, INC. (US) | 2007-07-05 | — | — | WO | disclosed |
| WO-2007075896-A2 | HETEROCYCLIC CYTOKINE INHIBITORS | KEMIA, INC. (US) | 2007-07-05 | — | — | WO | disclosed |