Predicted protein targets (top 4)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | RAF1 | P04049 | 17/20 | 0.58 |
| ▸ | BRAF | P15056 | 16/20 | 0.58 |
| ▸ | CSF1R | P07333 | 1/20 | 0.56 |
| ▸ | MAPK14 | Q16539 | 1/20 | 0.51 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5593303 | 0.85 | RAF1 (0.59) | RAF1BRAFMAPK14 | |
| SCHEMBL5593400 | 0.82 | RAF1 (0.46) | RAF1BRAFCSF1R | |
| SCHEMBL4829508 | 0.78 | CSF1R (0.68) | RAF1BRAFCSF1RMAPK14 | |
| SCHEMBL4552241 | 0.78 | RAF1 (0.63) | RAF1BRAFCSF1R | |
| SCHEMBL5593449 | 0.77 | CSF1R (0.57) | RAF1BRAFCSF1RMAPK14 | |
| SCHEMBL25534818 | 0.75 | CSF1R (0.71) | RAF1BRAFCSF1RMAPK14 | |
| SCHEMBL1420016 | 0.75 | RAF1 (0.65) | RAF1BRAFCSF1R | |
| SCHEMBL17523514 | 0.75 | RAF1 (0.80) | RAF1BRAFCSF1RMAPK14 | |
| SCHEMBL5592958 | 0.74 | MAPK14 (0.54) | RAF1BRAFMAPK14 | |
| SCHEMBL16035838 | 0.73 | BRAF (1.00) | RAF1BRAF |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2007075896-A2 | HETEROCYCLIC CYTOKINE INHIBITORS | KEMIA, INC. (US) | 2007-07-05 | — | — | WO | disclosed |