Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | RAB9A | P51151 | 7/20 | 0.66 |
| ▸ | NPC1 | O15118 | 5/20 | 0.66 |
| ▸ | SMN1; SMN2 | Q16637 | 5/20 | 0.55 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.55 |
| ▸ | HPGD | P15428 | 5/20 | 0.50 |
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.50 |
| ▸ | TP53 | P04637 | 1/20 | 0.50 |
| ▸ | ATM | Q13315 | 1/20 | 0.50 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.49 |
| ▸ | MCL1 | Q07820 | 1/20 | 0.49 |
| ▸ | MEN1 | O00255 | 1/20 | 0.49 |
| ▸ | LMNA | P02545 | 3/20 | 0.48 |
| ▸ | HTT | P42858 | 1/20 | 0.48 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.48 |
| ▸ | TSHR | P16473 | 1/20 | 0.47 |
| ▸ | HIF1A | Q16665 | 1/20 | 0.47 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.46 |
| ▸ | ALOX12 | P18054 | 1/20 | 0.46 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.46 |
| ▸ | GAA | P10253 | 1/20 | 0.46 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL14473326 | 0.81 | RAB9A (0.51) | RAB9ANPC1SMN1; SMN2L3MBTL1HPGD | |
| SCHEMBL14473018 | 0.80 | RAB9A (0.50) | RAB9ANPC1SMN1; SMN2HPGDALDH1A1 | |
| SCHEMBL5616693 | 0.79 | RAB9A (0.54) | RAB9ANPC1SMN1; SMN2HPGDALDH1A1 | |
| SCHEMBL17874024 | 0.78 | RAB9A (0.80) | RAB9ANPC1SMN1; SMN2L3MBTL1HPGD | |
| SCHEMBL5593407 | 0.77 | RAB9A (0.54) | RAB9ANPC1SMN1; SMN2HPGDALDH1A1 | |
| SCHEMBL5603883 | 0.77 | RAB9A (0.57) | RAB9ANPC1SMN1; SMN2L3MBTL1HPGD | |
| SCHEMBL5603888 | 0.76 | RAB9A (0.57) | RAB9ANPC1SMN1; SMN2HPGDALDH1A1 | |
| SCHEMBL4541476 | 0.76 | RAB9A (0.49) | RAB9ANPC1SMN1; SMN2L3MBTL1ALDH1A1 | |
| SCHEMBL4551381 | 0.76 | RAB9A (0.53) | RAB9ANPC1SMN1; SMN2L3MBTL1HPGD | |
| SCHEMBL4412422 | 0.76 | RAB9A (0.51) | RAB9ANPC1SMN1; SMN2L3MBTL1HPGD |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2007075896-A2 | HETEROCYCLIC CYTOKINE INHIBITORS | KEMIA, INC. (US) | 2007-07-05 | — | — | WO | disclosed |