Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | RAB9A | P51151 | 6/20 | 0.57 |
| ▸ | NPC1 | O15118 | 5/20 | 0.57 |
| ▸ | POLB | P06746 | 1/20 | 0.48 |
| ▸ | MAPT | P10636 | 1/20 | 0.48 |
| ▸ | HPGD | P15428 | 4/20 | 0.47 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.47 |
| ▸ | LMNA | P02545 | 2/20 | 0.47 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.47 |
| ▸ | ALDH1A1 | P00352 | 6/20 | 0.45 |
| ▸ | TSHR | P16473 | 1/20 | 0.45 |
| ▸ | ATM | Q13315 | 2/20 | 0.45 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.44 |
| ▸ | GAA | P10253 | 1/20 | 0.44 |
| ▸ | TP53 | P04637 | 1/20 | 0.44 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.43 |
| ▸ | HTT | P42858 | 1/20 | 0.42 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5603888 | 0.92 | RAB9A (0.57) | RAB9ANPC1POLBMAPTHPGD | |
| SCHEMBL5593473 | 0.77 | RAB9A (0.66) | RAB9ANPC1HPGDSMN1; SMN2LMNA | |
| SCHEMBL5593407 | 0.77 | RAB9A (0.54) | RAB9ANPC1POLBHPGDSMN1; SMN2 | |
| SCHEMBL5616693 | 0.77 | RAB9A (0.54) | RAB9ANPC1POLBHPGDSMN1; SMN2 | |
| SCHEMBL17874024 | 0.76 | RAB9A (0.80) | RAB9ANPC1POLBMAPTHPGD | |
| SCHEMBL5604188 | 0.74 | RAB9A (0.52) | RAB9ANPC1HPGDSMN1; SMN2LMNA | |
| SCHEMBL4551381 | 0.74 | RAB9A (0.53) | RAB9ANPC1POLBMAPTHPGD | |
| SCHEMBL4541476 | 0.74 | RAB9A (0.49) | RAB9ANPC1POLBSMN1; SMN2ALDH1A1 | |
| SCHEMBL26035489 | 0.73 | ATM (0.55) | RAB9ANPC1POLBMAPTHPGD | |
| SCHEMBL5603893 | 0.72 | RAB9A (0.46) | RAB9ANPC1POLBHPGDSMN1; SMN2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2007075896-A2 | HETEROCYCLIC CYTOKINE INHIBITORS | KEMIA, INC. (US) | 2007-07-05 | — | — | WO | disclosed |