Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ATR | Q13535 | 5/20 | 0.41 |
| ▸ | GAA | P10253 | 2/20 | 0.35 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.34 |
| ▸ | MAPT | P10636 | 1/20 | 0.34 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.34 |
| ▸ | HTT | P42858 | 1/20 | 0.34 |
| ▸ | RECQL | P46063 | 1/20 | 0.34 |
| ▸ | PTK2B | Q14289 | 1/20 | 0.34 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.33 |
| ▸ | POLB | P06746 | 2/20 | 0.33 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.33 |
| ▸ | LMNA | P02545 | 1/20 | 0.33 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.33 |
| ▸ | ACVRL1 | P37023 | 1/20 | 0.33 |
| ▸ | ACVR1 | Q04771 | 1/20 | 0.33 |
| ▸ | HRH4 | Q9H3N8 | 2/20 | 0.33 |
| ▸ | RET | P07949 | 1/20 | 0.33 |
| ▸ | TNK2 | Q07912 | 1/20 | 0.32 |
| ▸ | DGAT2 | Q96PD7 | 1/20 | 0.32 |
| ▸ | PDE7A | Q13946 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5593628 | 0.91 | IP6K1 (0.36) | ATRGAAKDM4EALDH1A1POLB | |
| SCHEMBL5605093 | 0.84 | ALDH1A1 (0.43) | ATRGAAMAPTHTTALDH1A1 | |
| SCHEMBL5612758 | 0.82 | BRPF1 (0.40) | ATRMAPTPOLB | |
| SCHEMBL5616695 | 0.81 | GAA (0.42) | ATRGAAALDH1A1POLBHSD17B10 | |
| SCHEMBL1024018 | 0.79 | GAA (0.42) | ATRGAAALDH1A1POLBHSD17B10 | |
| SCHEMBL5593861 | 0.77 | ATR (0.34) | ATRGAAKDM4EALDH1A1POLB | |
| SCHEMBL5604700 | 0.75 | ALDH1A1 (0.40) | GAAMAPTMAPK1HTTALDH1A1 | |
| SCHEMBL14863556 | 0.74 | ALDH1A1 (0.39) | ATRGAAKDM4EMAPTALDH1A1 | |
| SCHEMBL29388171 | 0.74 | ALDH1A1 (0.39) | ATRGAAKDM4EMAPTALDH1A1 | |
| SCHEMBL29096485 | 0.73 | ALDH1A1 (0.44) | ATRGAAMAPK1ALDH1A1POLB |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2007058626-A1 | INDAZOLE COMPOUNDS | S*BIO PTE LTD (SG) | 2007-05-24 | — | — | WO | disclosed |