Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 11/20 | 0.40 |
| ▸ | MAPT | P10636 | 8/20 | 0.40 |
| ▸ | HTT | P42858 | 1/20 | 0.40 |
| ▸ | CYP1A2 | P05177 | 2/20 | 0.40 |
| ▸ | CYP2C19 | P33261 | 2/20 | 0.40 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.40 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.40 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.40 |
| ▸ | GAA | P10253 | 4/20 | 0.38 |
| ▸ | LMNA | P02545 | 3/20 | 0.38 |
| ▸ | HSP90AA1 | P07900 | 1/20 | 0.38 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.38 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.38 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.38 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.38 |
| ▸ | POLB | P06746 | 2/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5605093 | 0.92 | ALDH1A1 (0.43) | ALDH1A1MAPTHTTCYP1A2CYP2C19 | |
| SCHEMBL5593784 | 0.86 | MAPT (0.44) | ALDH1A1MAPTHTTCYP1A2CYP2C19 | |
| SCHEMBL5593656 | 0.84 | KMT2A (0.36) | ALDH1A1MAPTCYP1A2CYP2C19CYP2C9 | |
| SCHEMBL5593876 | 0.84 | CYP1A2 (0.35) | ALDH1A1MAPTHTTCYP1A2SMN1; SMN2 | |
| SCHEMBL5593628 | 0.83 | IP6K1 (0.36) | ALDH1A1GAALMNAL3MBTL1POLB | |
| SCHEMBL1026761 | 0.82 | KMT2A (0.36) | ALDH1A1MAPTHTTCYP1A2CYP2C19 | |
| SCHEMBL31475214 | 0.77 | CYP1A2 (0.39) | ALDH1A1MAPTCYP1A2HSP90AA1SMN1; SMN2 | |
| SCHEMBL28686145 | 0.77 | SIRT2 (0.40) | ALDH1A1MAPTCYP1A2LMNASMN1; SMN2 | |
| SCHEMBL29643977 | 0.77 | SIRT2 (0.40) | ALDH1A1MAPTCYP1A2LMNASMN1; SMN2 | |
| SCHEMBL4048725 | 0.77 | CYP1A2 (0.39) | ALDH1A1MAPTCYP1A2HSP90AA1SMN1; SMN2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2007058626-A1 | INDAZOLE COMPOUNDS | S*BIO PTE LTD (SG) | 2007-05-24 | — | — | WO | disclosed |