Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPT | P10636 | 4/20 | 0.47 |
| ▸ | LMNA | P02545 | 2/20 | 0.47 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.47 |
| ▸ | NPC1 | O15118 | 1/20 | 0.47 |
| ▸ | TP53 | P04637 | 1/20 | 0.47 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.47 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.47 |
| ▸ | MAOA | P21397 | 1/20 | 0.47 |
| ▸ | SLC6A2 | P23975 | 1/20 | 0.47 |
| ▸ | RAB9A | P51151 | 1/20 | 0.47 |
| ▸ | SLC6A3 | Q01959 | 1/20 | 0.47 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.47 |
| ▸ | ESRRG | P62508 | 1/20 | 0.45 |
| ▸ | AOC3 | Q16853 | 1/20 | 0.42 |
| ▸ | HTT | P42858 | 1/20 | 0.41 |
| ▸ | TERT | O14746 | 1/20 | 0.41 |
| ▸ | CNR2 | P34972 | 1/20 | 0.40 |
| ▸ | PTPN1 | P18031 | 2/20 | 0.39 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.39 |
| ▸ | GAA | P10253 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5593638 | 0.86 | KDM4E (0.49) | MAPTLMNAKDM4ENPC1TP53 | |
| SCHEMBL21617914 | 0.85 | LMNA (0.60) | MAPTLMNAKDM4ENPC1TP53 | |
| SCHEMBL5593618 | 0.84 | CYP1A2 (0.49) | MAPTLMNAKDM4ENPC1TP53 | |
| SCHEMBL11334796 | 0.83 | THRA (0.53) | MAPTLMNANPC1CYP3A4RAB9A | |
| SCHEMBL13577590 | 0.82 | CYP1A2 (0.54) | MAPTLMNAKDM4ENPC1TP53 | |
| SCHEMBL16595321 | 0.80 | LMNA (0.51) | MAPTLMNAKDM4ENPC1TP53 | |
| SCHEMBL5348242 | 0.79 | CYP1A2 (0.57) | MAPTLMNAKDM4ENPC1TP53 | |
| SCHEMBL5593706 | 0.78 | MAPT (0.74) | MAPTLMNAKDM4ENPC1TP53 | |
| SCHEMBL4548368 | 0.78 | LMNA (0.53) | MAPTLMNAKDM4ENPC1TP53 | |
| SCHEMBL5593842 | 0.78 | CYP1A2 (0.53) | MAPTLMNAKDM4ENPC1TP53 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2007022263-A1 | FLUOROGENIC PROBES FOR MEDIUM CHAIN ACYL-COA DEHYDROGENASE ( MCAD ) | THE TRUSTEES OF COLUMBIA UNIVERSITY IN THE CITY OF NEW YORK (US) | 2007-02-22 | — | — | WO | disclosed |
| WO-2007022263-A1 | FLUOROGENIC PROBES FOR MEDIUM CHAIN ACYL-COA DEHYDROGENASE ( MCAD ) | THE TRUSTEES OF COLUMBIA UNIVERSITY IN THE CITY OF NEW YORK (US) | 2007-02-22 | — | — | WO | disclosed |