Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | THRA | P10827 | 1/20 | 0.53 |
| ▸ | THRB | P10828 | 1/20 | 0.53 |
| ▸ | SIRT2 | Q8IXJ6 | 1/20 | 0.47 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.46 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.46 |
| ▸ | CNR2 | P34972 | 2/20 | 0.44 |
| ▸ | BRD4 | O60885 | 1/20 | 0.42 |
| ▸ | MAPT | P10636 | 4/20 | 0.42 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.41 |
| ▸ | GFER | P55789 | 1/20 | 0.41 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.41 |
| ▸ | CYP11B1 | P15538 | 1/20 | 0.41 |
| ▸ | CYP11B2 | P19099 | 1/20 | 0.41 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.41 |
| ▸ | PTPN1 | P18031 | 2/20 | 0.41 |
| ▸ | LMNA | P02545 | 2/20 | 0.41 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.41 |
| ▸ | NPC1 | O15118 | 1/20 | 0.41 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.41 |
| ▸ | RAB9A | P51151 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11340512 | 0.87 | THRB (0.52) | THRATHRBALDH1A1CYP3A4MAPT | |
| SCHEMBL15709977 | 0.85 | SLC7A5 (0.50) | THRATHRBALDH1A1CYP3A4CNR2 | |
| SCHEMBL3679227 | 0.83 | THRA (0.67) | THRATHRBALDH1A1CYP3A4CNR2 | |
| SCHEMBL5593715 | 0.83 | MAPT (0.47) | ALDH1A1CYP3A4CNR2MAPTSMN1; SMN2 | |
| SCHEMBL11341527 | 0.82 | THRA (0.52) | THRATHRBALDH1A1CYP3A4CNR2 | |
| SCHEMBL11341529 | 0.82 | THRA (0.52) | THRATHRBALDH1A1CYP3A4CNR2 | |
| SCHEMBL19540906 | 0.80 | SIRT2 (0.52) | SIRT2ALDH1A1BRD4CYP11B1CYP11B2 | |
| SCHEMBL12255149 | 0.80 | SIRT2 (0.52) | SIRT2ALDH1A1BRD4MAPTCYP11B1 | |
| SCHEMBL901672 | 0.78 | TAAR1 (0.53) | SIRT2CNR2MAPTL3MBTL1 | |
| Hydrochloric Acid SCHEMBL11301081 | 0.77 | THRA (0.48) | THRATHRBALDH1A1CYP3A4CNR2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4243606-A | AZO DYE COUPLER INTERMEDIATES | PRODUITS CHIMIQUES UGINE KUHLMANN (FR) | 1981-01-06 | — | — | US | disclosed |