Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | AURKA | O14965 | 1/20 | 0.40 |
| ▸ | AURKB | Q96GD4 | 1/20 | 0.40 |
| ▸ | MAPT | P10636 | 7/20 | 0.37 |
| ▸ | ALDH1A1 | P00352 | 6/20 | 0.37 |
| ▸ | ALDH1A3 | P47895 | 1/20 | 0.37 |
| ▸ | ATR | Q13535 | 1/20 | 0.35 |
| ▸ | SMN1; SMN2 | Q16637 | 4/20 | 0.35 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.35 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.35 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.35 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.35 |
| ▸ | LMNA | P02545 | 5/20 | 0.35 |
| ▸ | PKM | P14618 | 1/20 | 0.35 |
| ▸ | HRH4 | Q9H3N8 | 1/20 | 0.34 |
| ▸ | ALOX12 | P18054 | 1/20 | 0.34 |
| ▸ | NPSR1 | Q6W5P4 | 2/20 | 0.33 |
| ▸ | HTT | P42858 | 2/20 | 0.33 |
| ▸ | GAA | P10253 | 1/20 | 0.33 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.33 |
| ▸ | MEN1 | O00255 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5605093 | 0.79 | ALDH1A1 (0.43) | MAPTALDH1A1ATRSMN1; SMN2CYP1A2 | |
| SCHEMBL5604700 | 0.72 | ALDH1A1 (0.40) | MAPTALDH1A1SMN1; SMN2CYP1A2CYP2D6 | |
| SCHEMBL5593784 | 0.70 | MAPT (0.44) | MAPTALDH1A1SMN1; SMN2CYP1A2CYP2D6 | |
| SCHEMBL5593679 | 0.69 | AURKA (0.36) | AURKAAURKBMAPTALDH1A1ATR | |
| SCHEMBL5593675 | 0.68 | MAPT (0.36) | AURKAAURKBMAPTALDH1A1ATR | |
| SCHEMBL5594186 | 0.68 | AURKA (0.38) | AURKAAURKBATR | |
| SCHEMBL5594285 | 0.67 | CYP4F2 (0.36) | MAPTALDH1A1ATRCYP1A2CYP2C9 | |
| SCHEMBL20247111 | 0.67 | FGFR4 (0.38) | AURKA | |
| SCHEMBL12821556 | 0.67 | CYP1A2 (0.38) | MAPTALDH1A1SMN1; SMN2CYP1A2LMNA | |
| SCHEMBL30804956 | 0.67 | CYP1A2 (0.38) | MAPTALDH1A1SMN1; SMN2CYP1A2LMNA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2007058626-A1 | INDAZOLE COMPOUNDS | S*BIO PTE LTD (SG) | 2007-05-24 | — | — | WO | disclosed |