Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPT | P10636 | 5/20 | 0.36 |
| ▸ | GAA | P10253 | 2/20 | 0.36 |
| ▸ | TP53 | P04637 | 2/20 | 0.36 |
| ▸ | AURKA | O14965 | 2/20 | 0.35 |
| ▸ | AURKB | Q96GD4 | 2/20 | 0.35 |
| ▸ | BRPF1 | P55201 | 3/20 | 0.35 |
| ▸ | DGAT2 | Q96PD7 | 1/20 | 0.34 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.33 |
| ▸ | POLB | P06746 | 2/20 | 0.33 |
| ▸ | MEN1 | O00255 | 2/20 | 0.33 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.33 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.33 |
| ▸ | ATR | Q13535 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5593679 | 0.91 | AURKA (0.36) | MAPTGAATP53AURKAAURKB | |
| SCHEMBL5593867 | 0.76 | AURKB (0.56) | AURKAAURKB | |
| SCHEMBL5594265 | 0.76 | BRPF1 (0.36) | MAPTGAATP53BRPF1DGAT2 | |
| SCHEMBL5593774 | 0.68 | AURKA (0.40) | MAPTGAAAURKAAURKBALDH1A1 | |
| SCHEMBL5593778 | 0.66 | AURKA (0.45) | MAPTAURKAAURKBALDH1A1POLB | |
| SCHEMBL5593870 | 0.66 | AURKB (0.58) | AURKAAURKB | |
| SCHEMBL5594245 | 0.65 | AURKB (0.70) | AURKAAURKB | |
| SCHEMBL23533529 | 0.64 | RXRA (0.42) | ATR | |
| SCHEMBL23533527 | 0.64 | RXRA (0.42) | ATR | |
| SCHEMBL30632780 | 0.64 | OPRK1 (0.39) | DGAT2ATR |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2007058626-A1 | INDAZOLE COMPOUNDS | S*BIO PTE LTD (SG) | 2007-05-24 | — | — | WO | disclosed |