Predicted protein targets (top 12)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TERT | O14746 | 1/20 | 0.45 |
| ▸ | FAAH | O00519 | 11/20 | 0.44 |
| ▸ | ACKR3 | P25106 | 1/20 | 0.44 |
| ▸ | TBK1 | Q9UHD2 | 1/20 | 0.44 |
| ▸ | IDO1 | P14902 | 1/20 | 0.43 |
| ▸ | TDO2 | P48775 | 1/20 | 0.43 |
| ▸ | IDO2 | Q6ZQW0 | 1/20 | 0.43 |
| ▸ | VEGFA | P15692 | 1/20 | 0.43 |
| ▸ | EGLN1 | Q9GZT9 | 1/20 | 0.43 |
| ▸ | SMARCA2 | P51531 | 1/20 | 0.42 |
| ▸ | SMARCA4 | P51532 | 1/20 | 0.42 |
| ▸ | PBRM1 | Q86U86 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3588175 | 0.84 | FAAH (0.62) | FAAH | |
| SCHEMBL29126340 | 0.81 | CTSB (0.45) | TBK1IDO1TDO2IDO2VEGFA | |
| SCHEMBL617183 | 0.80 | FAAH (0.47) | TERTFAAHACKR3VEGFAEGLN1 | |
| SCHEMBL29126410 | 0.79 | MCHR1 (0.44) | FAAHTBK1 | |
| SCHEMBL17276352 | 0.78 | FAAH (0.58) | FAAH | |
| SCHEMBL16855862 | 0.78 | FAAH (0.58) | FAAH | |
| SCHEMBL2194827 | 0.76 | KDM1A (0.57) | IDO1TDO2IDO2VEGFAEGLN1 | |
| SCHEMBL30520640 | 0.75 | MEN1 (0.50) | TBK1IDO1TDO2IDO2VEGFA | |
| SCHEMBL16892052 | 0.75 | VEGFA (0.50) | TBK1VEGFAEGLN1 | |
| SCHEMBL18191713 | 0.75 | PIK3CA (0.46) | TBK1VEGFAEGLN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1189606-B1 | NOVEL IRON CHELATORS AND PHARMACEUTICAL COMPOSITIONS COMPRISING IRON CHELATORS FOR THE TREATMENT OF NEURODEGENERATIVE DISORDERS | YEDA RES & DEV (IL) | 2007-08-15 | — | — | EP | claimed |