Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LTA4H | P09960 | 9/20 | 0.54 |
| ▸ | ROCK2 | O75116 | 2/20 | 0.50 |
| ▸ | ARHGDIA | P52565 | 2/20 | 0.50 |
| ▸ | ROCK1 | Q13464 | 2/20 | 0.50 |
| ▸ | OPRM1 | P35372 | 1/20 | 0.46 |
| ▸ | OPRD1 | P41143 | 1/20 | 0.46 |
| ▸ | OPRK1 | P41145 | 1/20 | 0.46 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.46 |
| ▸ | DRD2 | P14416 | 1/20 | 0.45 |
| ▸ | DRD4 | P21917 | 1/20 | 0.45 |
| ▸ | SLC6A2 | P23975 | 1/20 | 0.45 |
| ▸ | DRD3 | P35462 | 1/20 | 0.45 |
| ▸ | MEN1 | O00255 | 1/20 | 0.44 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.44 |
| ▸ | CHRM2 | P08172 | 1/20 | 0.43 |
| ▸ | CHRM4 | P08173 | 1/20 | 0.43 |
| ▸ | CHRM5 | P08912 | 1/20 | 0.43 |
| ▸ | MAPT | P10636 | 1/20 | 0.43 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL14439615 | 1.00 | LTA4H (0.54) | LTA4HROCK2ARHGDIAROCK1OPRM1 | |
| SCHEMBL5595279 | 1.00 | LTA4H (0.54) | LTA4HROCK2ARHGDIAROCK1OPRM1 | |
| SCHEMBL6758155 | 0.89 | LTA4H (0.65) | LTA4HROCK2ARHGDIAROCK1OPRM1 | |
| SCHEMBL6758154 | 0.89 | LTA4H (0.65) | LTA4HROCK2ARHGDIAROCK1OPRM1 | |
| SCHEMBL5240088 | 0.77 | DRD4 (0.48) | DRD2DRD4SLC6A2DRD3CHRM2 | |
| SCHEMBL636999 | 0.76 | CHRM2 (0.58) | LTA4HDRD2DRD4DRD3MEN1 | |
| SCHEMBL7495709 | 0.75 | DRD4 (0.41) | LTA4HOPRK1DRD2DRD4SLC6A2 | |
| SCHEMBL8329958 | 0.75 | DRD4 (0.41) | LTA4HOPRK1DRD2DRD4SLC6A2 | |
| SCHEMBL7491794 | 0.75 | DRD4 (0.41) | LTA4HOPRK1DRD2DRD4SLC6A2 | |
| SCHEMBL15421001 | 0.74 | CHRM2 (0.57) | LTA4HOPRM1OPRK1KCNH2DRD4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20070196270-A1 | Compounds As Ccri Antagonists | HENG RICHARD | 2007-08-23 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20070196270-A1 | Compounds As Ccri Antagonists | CCR1, CCR10, CCR4 | LTA4H 417/4885ROCK2 3668/4885ARHGDIA 1327/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.