Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LMNA | P02545 | 4/20 | 0.61 |
| ▸ | CES2 | O00748 | 1/20 | 0.61 |
| ▸ | CES1 | P23141 | 1/20 | 0.61 |
| ▸ | ALDH1A1 | P00352 | 7/20 | 0.57 |
| ▸ | NPSR1 | Q6W5P4 | 2/20 | 0.57 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.57 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.57 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.57 |
| ▸ | CYP3A4 | P08684 | 3/20 | 0.53 |
| ▸ | ADRA2C | P18825 | 2/20 | 0.53 |
| ▸ | TSHR | P16473 | 2/20 | 0.53 |
| ▸ | CYP2C19 | P33261 | 2/20 | 0.53 |
| ▸ | CHRM2 | P08172 | 1/20 | 0.53 |
| ▸ | ADRA1A | P35348 | 1/20 | 0.53 |
| ▸ | RGS12 | O14924 | 1/20 | 0.53 |
| ▸ | GLA | P06280 | 1/20 | 0.53 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.53 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.53 |
| ▸ | PKM | P14618 | 1/20 | 0.53 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.53 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL13039632 | 0.84 | LMNA (0.56) | LMNACES2CES1ALDH1A1NPSR1 | |
| SCHEMBL28441543 | 0.83 | LMNA (0.57) | LMNACES2CES1ALDH1A1NPSR1 | |
| SCHEMBL5596165 | 0.83 | UGT2B7 (0.54) | LMNACES2CES1ALDH1A1NPSR1 | |
| SCHEMBL8209874 | 0.83 | LMNA (0.56) | LMNAALDH1A1NPSR1TDP1CYP3A4 | |
| SCHEMBL8001841 | 0.83 | LMNA (0.56) | LMNAALDH1A1NPSR1TDP1CYP3A4 | |
| SCHEMBL17702817 | 0.83 | LMNA (0.56) | LMNAALDH1A1NPSR1TDP1CYP3A4 | |
| SCHEMBL28229063 | 0.83 | LMNA (0.56) | LMNAALDH1A1NPSR1TDP1CYP3A4 | |
| SCHEMBL12265956 | 0.83 | LMNA (0.56) | LMNAALDH1A1NPSR1TDP1CYP3A4 | |
| SCHEMBL12313665 | 0.83 | LMNA (0.56) | LMNAALDH1A1NPSR1TDP1CYP3A4 | |
| SCHEMBL8001842 | 0.83 | LMNA (0.56) | LMNAALDH1A1NPSR1TDP1CYP3A4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 11 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1153657-B1 | METHOD OF IDENTIFYING AN AQUEOUS SYSTEM LEWIS ACID CATALYST FOR THE ALDOL REACTION. | JAPAN SCIENCE & TECH AGENCY (JP) | 2009-09-09 | — | — | EP | disclosed |
| EP-1375464-B1 | METHOD FOR ALDOL REACTION IN WATER | JAPAN SCIENCE & TECH AGENCY (JP) | 2009-03-04 | — | — | EP | disclosed |
| US-7323603-B2 | Reacting an aldehyde with a silyl enol ether in an aqueous medium in the presence of a boronic acid, a surfactant, and a Bronsted acid | JAPAN SCIENCE AND TECHNOLOGY CORPORATION (JP) | 2008-01-29 | — | — | US | disclosed |
| US-7323603-B2 | Reacting an aldehyde with a silyl enol ether in an aqueous medium in the presence of a boronic acid, a surfactant, and a Bronsted acid | JAPAN SCIENCE AND TECHNOLOGY CORPORATION (JP) | 2008-01-29 | — | — | US | disclosed |
| US-20070238902-A1 | Method for Performing Aldol Reaction in Water | JAPAN SCIENCE AND TECHNOLOGY AGENCY (JP) | 2007-10-11 | — | — | US | disclosed |
| US-20070238902-A1 | Method for Performing Aldol Reaction in Water | JAPAN SCIENCE AND TECHNOLOGY AGENCY (JP) | 2007-10-11 | — | — | US | disclosed |
| EP-1203616-B1 | CHIRAL LEAD CATALYST AND METHOD OF ASYMMETRIC ALDOL REACTION | JAPAN SCIENCE & TECH AGENCY (JP) | 2007-01-10 | — | — | EP | disclosed |
| US-6780812-B2 | SUCH AS LEAD TRIFLATE AND A CHIRAL CROWN ETHER COMPOUND | JAPAN SCIENCE AND TECHNOLOGY CORPORATION (JP) | 2004-08-24 | — | — | US | disclosed |
| US-20040087437-A1 | CHIRAL LEAD CATALYST AND METHOD OF ASYMMETRIC ALDOL REACTION | JAPAN SCIENCE AND TECHNOLOGY CORPORATION (JP) | 2004-05-06 | — | — | US | disclosed |
| EP-1203616-A1 | CHIRAL LEAD CATALYST AND METHOD OF ASYMMETRIC ALDOL REACTION | Japan Science and Technology Corporation (JP) | 2002-05-08 | — | — | EP | disclosed |
| EP-0386650-A2 | Aqueous disperse systems of photoinitiators and their use | LAMBERTI S.p.A. (IT) | 1990-09-12 | — | — | EP | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20070238902-A1 | Method for Performing Aldol Reaction in Water | AKR1C3, ADH1C, ADH5 | LMNA 1985/4885CES2 1241/4885CES1 1034/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.