Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.49 |
| ▸ | MEN1 | O00255 | 2/20 | 0.48 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.48 |
| ▸ | MAOA | P21397 | 1/20 | 0.48 |
| ▸ | MAOB | P27338 | 1/20 | 0.48 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.47 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.47 |
| ▸ | PLAU | P00749 | 1/20 | 0.46 |
| ▸ | MAPT | P10636 | 1/20 | 0.46 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.46 |
| ▸ | DPP8 | Q6V1X1 | 1/20 | 0.45 |
| ▸ | DPP9 | Q86TI2 | 1/20 | 0.45 |
| ▸ | CYP19A1 | P11511 | 1/20 | 0.44 |
| ▸ | RAB9A | P51151 | 1/20 | 0.44 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Hydrochloric Acid SCHEMBL5595266 | 0.99 | ALDH1A1 (0.48) | ALDH1A1MEN1KMT2AMAOAMAOB | |
| SCHEMBL4624244 | 0.83 | ALDH1A1 (0.56) | ALDH1A1MEN1KMT2AMAPK1L3MBTL1 | |
| SCHEMBL7860569 | 0.83 | RAB9A (0.52) | ALDH1A1PLAUMAPTDPP8DPP9 | |
| SCHEMBL27388024 | 0.82 | IDO1 (0.51) | ALDH1A1MEN1KMT2AMAPK1MAPT | |
| SCHEMBL6966891 | 0.81 | PLAU (0.59) | MEN1KMT2APLAUMAPTSMN1; SMN2 | |
| SCHEMBL14524520 | 0.80 | CYP1A2 (0.50) | ALDH1A1MEN1KMT2AMAPTSMN1; SMN2 | |
| SCHEMBL9878297 | 0.80 | DPP8 (0.47) | ALDH1A1PLAUMAPTDPP8DPP9 | |
| SCHEMBL11630406 | 0.80 | L3MBTL1 (0.58) | ALDH1A1MEN1KMT2AMAOAMAOB | |
| SCHEMBL6053078 | 0.80 | PLAU (0.72) | PLAUDPP8DPP9RAB9A | |
| Hydrochloric Acid SCHEMBL5595269 | 0.79 | PLAU (0.70) | PLAUDPP8DPP9 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 8 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-7208521-B2 | Selective inhibitors of the urokinase plasminogen activator | WILEX AG (DE) | 2007-04-24 | — | — | US | disclosed |
| US-7208521-B2 | Selective inhibitors of the urokinase plasminogen activator | WILEX AG (DE) | 2007-04-24 | — | — | US | disclosed |
| US-7208521-B2 | Selective inhibitors of the urokinase plasminogen activator | WILEX AG (DE) | 2007-04-24 | — | — | US | disclosed |
| US-7049460-B1 | Selective inhibitors of the urokinase plasminogen activator | WILEX AG (DE) | 2006-05-23 | — | — | US | disclosed |
| US-20050215642-A1 | Selective inhibitors of the urokinase plasminogen activator | WILEX AG (DE) | 2005-09-29 | — | — | US | disclosed |
| EP-1206447-B1 | SELECTIVE INHIBITORS OF THE UROKINASE PLASMINOGENE ACTIVATORS | WILEX AG (DE) | 2004-02-25 | — | — | EP | disclosed |
| EP-1206447-A1 | SELECTIVE INHIBITORS OF THE UROKINASE PLASMINOGENE ACTIVATORS | Wilex Biotechnology GmbH (DE) | 2002-05-22 | — | — | EP | disclosed |
| WO-2001014324-A1 | SELECTIVE INHIBITORS OF THE UROKINASE PLASMINOGENE ACTIVATORS | WILEX AG (DE) | 2001-03-01 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20050215642-A1 | Selective inhibitors of the urokinase plasminogen activator | PLAU, SERPINE1, PLAUR | ALDH1A1 1423/4885MEN1 3295/4885KMT2A 3194/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.