Predicted protein targets (top 6)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CES2 | O00748 | 1/20 | 0.50 |
| ▸ | FAAH | O00519 | 2/20 | 0.38 |
| ▸ | ENPP2 | Q13822 | 4/20 | 0.37 |
| ▸ | MEN1 | O00255 | 1/20 | 0.37 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.37 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5595795 | 0.92 | LPAR2 (0.44) | FAAHENPP2MEN1KMT2A | |
| SCHEMBL5595580 | 0.75 | LPAR2 (0.53) | FAAHMEN1KMT2A | |
| SCHEMBL11644166 | 0.72 | CES2 (0.53) | CES2FAAHMEN1MAPK1KMT2A | |
| SCHEMBL11863469 | 0.70 | MAPT (0.53) | CES2FAAH | |
| Octadecanoic Acid Amide SCHEMBL28119755 | 0.69 | SOAT1 (0.42) | FAAHENPP2MEN1KMT2A | |
| SCHEMBL6384367 | 0.68 | CES2 (1.00) | CES2MEN1KMT2A | |
| SCHEMBL8584172 | 0.68 | CES2 (0.62) | CES2 | |
| SCHEMBL11626606 | 0.68 | KMT2A (0.48) | CES2MEN1KMT2A | |
| SCHEMBL7563843 | 0.68 | KMT2A (0.48) | CES2MEN1KMT2A | |
| SCHEMBL7950973 | 0.68 | KMT2A (0.48) | CES2MEN1KMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20070123492-A1 | Analogs of lysophosphatidic acid and methods of making and using thereof | NATIONAL INSTITUTES OF HEALTH - DIRECTOR DEITR | 2007-05-31 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20070123492-A1 | Analogs of lysophosphatidic acid and methods of making and using thereof | LPAR4, LPAR2, LPAR5 | CES2 969/4885FAAH 299/4885ENPP2 20/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.