Predicted protein targets (top 7)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CES2 | O00748 | 2/20 | 0.53 |
| ▸ | LMNA | P02545 | 3/20 | 0.39 |
| ▸ | FAAH | O00519 | 2/20 | 0.39 |
| ▸ | CES1 | P23141 | 1/20 | 0.39 |
| ▸ | MEN1 | O00255 | 1/20 | 0.38 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.38 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8583777 | 0.79 | CES2 (0.59) | CES2 | |
| SCHEMBL7168676 | 0.79 | CES2 (0.44) | CES2LMNACES1 | |
| SCHEMBL11718680 | 0.79 | CES2 (0.44) | CES2LMNAFAAHCES1MEN1 | |
| SCHEMBL10493704 | 0.79 | CES2 (0.44) | CES2LMNAFAAHCES1MEN1 | |
| SCHEMBL8581732 | 0.78 | CES2 (0.62) | CES2 | |
| SCHEMBL8584172 | 0.78 | CES2 (0.62) | CES2 | |
| SCHEMBL11711111 | 0.77 | CES2 (0.47) | CES2CES1 | |
| SCHEMBL8961229 | 0.73 | LMNA (0.40) | CES2LMNACES1 | |
| SCHEMBL5595680 | 0.72 | CES2 (0.50) | CES2FAAHMEN1MAPK1KMT2A | |
| SCHEMBL6384367 | 0.70 | CES2 (1.00) | CES2CES1MEN1KMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4112225-A | 16-CF3 prostaglandins | HOFFMAN-LA ROCHE INC. (US) | 1978-09-05 | — | — | US | disclosed |