Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CYP2D6 | P10635 | 2/20 | 0.47 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.46 |
| ▸ | HPGD | P15428 | 1/20 | 0.46 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.46 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.46 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.46 |
| ▸ | MAPT | P10636 | 2/20 | 0.42 |
| ▸ | MEN1 | O00255 | 1/20 | 0.42 |
| ▸ | GAA | P10253 | 1/20 | 0.42 |
| ▸ | PKM | P14618 | 1/20 | 0.42 |
| ▸ | RECQL | P46063 | 1/20 | 0.42 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.42 |
| ▸ | TSHR | P16473 | 1/20 | 0.40 |
| ▸ | ESR1 | P03372 | 1/20 | 0.39 |
| ▸ | ESR2 | Q92731 | 1/20 | 0.39 |
| ▸ | RAB9A | P51151 | 2/20 | 0.38 |
| ▸ | LMNA | P02545 | 1/20 | 0.38 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.37 |
| ▸ | HSP90AA1 | P07900 | 1/20 | 0.37 |
| ▸ | HSP90AB1 | P08238 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5596853 | 0.79 | TRPA1 (0.41) | ALDH1A1HPGDALOX15HSD17B10TDP1 | |
| SCHEMBL5596196 | 0.78 | ALDH1A1 (0.53) | CYP2D6ALDH1A1HPGDALOX15HSD17B10 | |
| SCHEMBL5596113 | 0.76 | ALDH1A1 (0.50) | CYP2D6ALDH1A1HPGDALOX15HSD17B10 | |
| SCHEMBL5596033 | 0.76 | ALDH1A1 (0.50) | CYP2D6ALDH1A1HPGDALOX15HSD17B10 | |
| SCHEMBL5596855 | 0.74 | AKR1B1 (0.39) | ALDH1A1HPGDALOX15HSD17B10TDP1 | |
| SCHEMBL5596154 | 0.73 | ALDH1A1 (0.47) | CYP2D6ALDH1A1HPGDALOX15HSD17B10 | |
| SCHEMBL11092652 | 0.72 | CYP2D6 (0.62) | CYP2D6ALDH1A1HPGDALOX15HSD17B10 | |
| SCHEMBL5596191 | 0.72 | ALDH1A1 (0.59) | CYP2D6ALDH1A1HPGDALOX15HSD17B10 | |
| SCHEMBL28831112 | 0.71 | CYP2D6 (0.60) | CYP2D6ALDH1A1HPGDALOX15HSD17B10 | |
| SCHEMBL5596647 | 0.71 | ALDH1A1 (0.44) | CYP2D6ALDH1A1HPGDALOX15HSD17B10 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-7279537-B2 | Transition metal complexes and polymerization catalysts | SUMITOMO CHEMICAL COMPANY, LIMITED (JP) | 2007-10-09 | — | — | US | disclosed |
| US-20060229195-A1 | Transition metal complexes and polymerization catalysts | SUMITOMO CHEMICAL COMPANY, LIMITED (JP) | 2006-10-12 | — | — | US | disclosed |
| EP-1557423-A1 | TRANSITION METAL COMPLEXES AND POLYMERIZATION CATALYSTS | Sumitomo Chemical Company, Limited (JP) | 2005-07-27 | — | — | EP | disclosed |