Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.50 |
| ▸ | MAPT | P10636 | 2/20 | 0.50 |
| ▸ | MEN1 | O00255 | 2/20 | 0.50 |
| ▸ | GAA | P10253 | 2/20 | 0.50 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.50 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.50 |
| ▸ | PKM | P14618 | 1/20 | 0.50 |
| ▸ | RECQL | P46063 | 1/20 | 0.50 |
| ▸ | HPGD | P15428 | 1/20 | 0.50 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.50 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.50 |
| ▸ | CYP2D6 | P10635 | 2/20 | 0.46 |
| ▸ | ESR1 | P03372 | 6/20 | 0.42 |
| ▸ | ESR2 | Q92731 | 5/20 | 0.42 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.40 |
| ▸ | TSHR | P16473 | 1/20 | 0.40 |
| ▸ | HDAC4 | P56524 | 1/20 | 0.40 |
| ▸ | HDAC2 | Q92769 | 1/20 | 0.40 |
| ▸ | HDAC8 | Q9BY41 | 1/20 | 0.40 |
| ▸ | HSD17B2 | P37059 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5596301 | 0.83 | ALDH1A1 (0.44) | ALDH1A1MAPTMEN1GAAKMT2A | |
| SCHEMBL25060874 | 0.79 | HSP90AA1 (0.43) | ALDH1A1MAPTMEN1GAAKMT2A | |
| SCHEMBL5596542 | 0.77 | ALOX15 (0.45) | ALDH1A1MAPTMEN1GAAKMT2A | |
| SCHEMBL5596191 | 0.76 | ALDH1A1 (0.59) | ALDH1A1MAPTMEN1GAAKMT2A | |
| SCHEMBL14883993 | 0.76 | TDP1 (0.41) | ALDH1A1MAPTTDP1SMN1; SMN2HDAC8 | |
| SCHEMBL18287343 | 0.76 | ALDH1A1 (0.37) | ALDH1A1TDP1HPGDALOX15HSD17B10 | |
| SCHEMBL5596202 | 0.76 | CYP2D6 (0.47) | ALDH1A1MAPTMEN1GAAKMT2A | |
| SCHEMBL29930505 | 0.75 | CYP2D6 (0.39) | ALDH1A1TDP1HPGDALOX15HSD17B10 | |
| SCHEMBL23581100 | 0.75 | CYP2D6 (0.39) | ALDH1A1TDP1HPGDALOX15HSD17B10 | |
| SCHEMBL10154127 | 0.75 | TDP1 (0.35) | ALDH1A1MAPTMEN1GAAKMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-7279537-B2 | Transition metal complexes and polymerization catalysts | SUMITOMO CHEMICAL COMPANY, LIMITED (JP) | 2007-10-09 | — | — | US | disclosed |
| US-20060229195-A1 | Transition metal complexes and polymerization catalysts | SUMITOMO CHEMICAL COMPANY, LIMITED (JP) | 2006-10-12 | — | — | US | disclosed |
| EP-1557423-A1 | TRANSITION METAL COMPLEXES AND POLYMERIZATION CATALYSTS | Sumitomo Chemical Company, Limited (JP) | 2005-07-27 | — | — | EP | disclosed |