Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.42 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.42 |
| ▸ | GAA | P10253 | 2/20 | 0.42 |
| ▸ | MAPT | P10636 | 2/20 | 0.42 |
| ▸ | LMNA | P02545 | 1/20 | 0.42 |
| ▸ | CA2 | P00918 | 2/20 | 0.34 |
| ▸ | SELL | P14151 | 1/20 | 0.34 |
| ▸ | SELP | P16109 | 1/20 | 0.34 |
| ▸ | SELE | P16581 | 1/20 | 0.34 |
| ▸ | CA1 | P00915 | 1/20 | 0.34 |
| ▸ | PKM | P14618 | 1/20 | 0.33 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.33 |
| ▸ | ESR1 | P03372 | 1/20 | 0.32 |
| ▸ | ESR2 | Q92731 | 1/20 | 0.32 |
| ▸ | NR3C1 | P04150 | 1/20 | 0.32 |
| ▸ | PGR | P06401 | 1/20 | 0.32 |
| ▸ | NR3C2 | P08235 | 1/20 | 0.32 |
| ▸ | HMGB1 | P09429 | 1/20 | 0.32 |
| ▸ | CXCL12 | P48061 | 1/20 | 0.32 |
| ▸ | PTGS1 | P23219 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5294769 | 0.82 | ALDH1A1 (0.43) | ALDH1A1KDM4EGAAMAPTLMNA | |
| SCHEMBL10454719 | 0.80 | ALDH1A1 (0.42) | ALDH1A1KDM4EGAAMAPTLMNA | |
| SCHEMBL39508 | 0.78 | ALOX15 (0.47) | ALDH1A1KDM4EGAAMAPTLMNA | |
| SCHEMBL29358673 | 0.78 | ALOX15 (0.47) | ALDH1A1KDM4EGAAMAPTLMNA | |
| SCHEMBL12510579 | 0.78 | ALDH1A1 (0.41) | ALDH1A1KDM4EGAAMAPTLMNA | |
| SCHEMBL5596277 | 0.78 | CYP3A4 (0.38) | ALDH1A1KDM4EGAAMAPTCA2 | |
| SCHEMBL5596390 | 0.78 | HPGD (0.46) | ALDH1A1GAAPTGS1PTGS2TP53 | |
| SCHEMBL12430319 | 0.77 | ALDH1A1 (0.39) | ALDH1A1KDM4EGAAMAPTLMNA | |
| SCHEMBL14493502 | 0.77 | ALOX15 (0.46) | ALDH1A1KDM4EGAAMAPTLMNA | |
| SCHEMBL5596195 | 0.77 | ALDH1A1 (0.46) | ALDH1A1KDM4EGAAMAPTLMNA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-7279537-B2 | Transition metal complexes and polymerization catalysts | SUMITOMO CHEMICAL COMPANY, LIMITED (JP) | 2007-10-09 | — | — | US | disclosed |
| US-20060229195-A1 | Transition metal complexes and polymerization catalysts | SUMITOMO CHEMICAL COMPANY, LIMITED (JP) | 2006-10-12 | — | — | US | disclosed |
| EP-1557423-A1 | TRANSITION METAL COMPLEXES AND POLYMERIZATION CATALYSTS | Sumitomo Chemical Company, Limited (JP) | 2005-07-27 | — | — | EP | disclosed |