Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CYP3A4 | P08684 | 3/20 | 0.38 |
| ▸ | HPGD | P15428 | 2/20 | 0.37 |
| ▸ | ALOX5 | P09917 | 2/20 | 0.37 |
| ▸ | PTGS1 | P23219 | 1/20 | 0.37 |
| ▸ | PTGS2 | P35354 | 1/20 | 0.37 |
| ▸ | PTPN1 | P18031 | 2/20 | 0.36 |
| ▸ | ADRA2A | P08913 | 1/20 | 0.36 |
| ▸ | ADRA1A | P35348 | 1/20 | 0.36 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.36 |
| ▸ | POLB | P06746 | 2/20 | 0.36 |
| ▸ | CA1 | P00915 | 1/20 | 0.35 |
| ▸ | CA2 | P00918 | 1/20 | 0.35 |
| ▸ | MEN1 | O00255 | 2/20 | 0.33 |
| ▸ | TSHR | P16473 | 1/20 | 0.33 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.33 |
| ▸ | HTT | P42858 | 1/20 | 0.33 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.33 |
| ▸ | GAA | P10253 | 1/20 | 0.33 |
| ▸ | MAPT | P10636 | 1/20 | 0.33 |
| ▸ | G6PD | P11413 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5596167 | 0.80 | CYP3A4 (0.42) | CYP3A4HPGDALOX5PTGS1PTGS2 | |
| SCHEMBL5596232 | 0.78 | ALDH1A1 (0.42) | HPGDPTGS1PTGS2POLBCA1 | |
| SCHEMBL5596374 | 0.75 | CA1 (0.42) | CYP3A4HPGDALOX5PTGS1PTGS2 | |
| SCHEMBL3047027 | 0.74 | CYP3A4 (0.56) | CYP3A4HPGDALOX5PTGS1PTGS2 | |
| SCHEMBL20620370 | 0.71 | CYP3A4 (0.37) | CYP3A4HPGDALOX5PTGS1PTGS2 | |
| SCHEMBL5596390 | 0.69 | HPGD (0.46) | CYP3A4HPGDPTGS1PTGS2TSHR | |
| SCHEMBL10106588 | 0.69 | CYP3A4 (0.62) | CYP3A4HPGDALOX5PTGS1PTGS2 | |
| SCHEMBL15894600 | 0.68 | CYP3A4 (0.45) | CYP3A4HPGDALOX5PTGS1PTGS2 | |
| SCHEMBL15247543 | 0.68 | CYP3A4 (0.45) | CYP3A4HPGDALOX5PTGS1PTGS2 | |
| SCHEMBL5596052 | 0.68 | ALDH1A1 (0.52) | CYP3A4HPGDPTGS1KMT2ACA1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-7279537-B2 | Transition metal complexes and polymerization catalysts | SUMITOMO CHEMICAL COMPANY, LIMITED (JP) | 2007-10-09 | — | — | US | disclosed |
| US-20060229195-A1 | Transition metal complexes and polymerization catalysts | SUMITOMO CHEMICAL COMPANY, LIMITED (JP) | 2006-10-12 | — | — | US | disclosed |
| EP-1557423-A1 | TRANSITION METAL COMPLEXES AND POLYMERIZATION CATALYSTS | Sumitomo Chemical Company, Limited (JP) | 2005-07-27 | — | — | EP | disclosed |