Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.44 |
| ▸ | MAPT | P10636 | 2/20 | 0.44 |
| ▸ | LMNA | P02545 | 1/20 | 0.44 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.44 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.44 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.44 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.44 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.44 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.43 |
| ▸ | S1PR2 | O95136 | 1/20 | 0.43 |
| ▸ | GAA | P10253 | 1/20 | 0.43 |
| ▸ | HPGD | P15428 | 1/20 | 0.43 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.43 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.43 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.43 |
| ▸ | NPC1 | O15118 | 1/20 | 0.40 |
| ▸ | RAB9A | P51151 | 1/20 | 0.40 |
| ▸ | EPHX2 | P34913 | 1/20 | 0.39 |
| ▸ | ILK | Q13418 | 1/20 | 0.38 |
| ▸ | CDK1 | P06493 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5596896 | 0.88 | CSNK1D (0.45) | ALDH1A1MAPTLMNACYP1A2CYP3A4 | |
| SCHEMBL5596256 | 0.86 | NPC1 (0.54) | ALDH1A1MAPTLMNACYP1A2CYP3A4 | |
| SCHEMBL5596418 | 0.85 | NPC1 (0.44) | ALDH1A1MAPTLMNACYP1A2CYP3A4 | |
| SCHEMBL5596674 | 0.85 | NPC1 (0.44) | ALDH1A1MAPTLMNACYP1A2CYP3A4 | |
| SCHEMBL5596937 | 0.85 | ILK (0.53) | ALDH1A1MAPTLMNACYP1A2CYP3A4 | |
| SCHEMBL5596939 | 0.85 | NPC1 (0.44) | ALDH1A1MAPTLMNACYP1A2CYP3A4 | |
| SCHEMBL5597099 | 0.84 | PTGS1 (0.46) | ALDH1A1MAPTLMNACYP1A2CYP3A4 | |
| SCHEMBL5597098 | 0.82 | MAPT (0.49) | ALDH1A1MAPTLMNAKDM4EHPGD | |
| SCHEMBL5596411 | 0.82 | RAB9A (0.45) | ALDH1A1MAPTLMNACYP1A2CYP3A4 | |
| SCHEMBL5596942 | 0.79 | ILK (0.51) | ALDH1A1MAPTLMNAKDM4EGAA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1696909-B1 | BENZOTHIAZOLE DERIVATIVES FOR THE TREATMENT OF DIABETES | SERONO LAB (CH) | 2007-11-14 | — | — | EP | claimed |