Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CYP3A4 | P08684 | 3/20 | 0.42 |
| ▸ | HPGD | P15428 | 2/20 | 0.40 |
| ▸ | ALOX5 | P09917 | 2/20 | 0.40 |
| ▸ | PTGS1 | P23219 | 1/20 | 0.40 |
| ▸ | PTGS2 | P35354 | 1/20 | 0.40 |
| ▸ | PTPN1 | P18031 | 2/20 | 0.39 |
| ▸ | CA1 | P00915 | 2/20 | 0.38 |
| ▸ | CA2 | P00918 | 2/20 | 0.38 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.37 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.35 |
| ▸ | POLB | P06746 | 2/20 | 0.35 |
| ▸ | ABL1 | P00519 | 2/20 | 0.34 |
| ▸ | BCR | P11274 | 2/20 | 0.34 |
| ▸ | ABCB1 | P08183 | 1/20 | 0.33 |
| ▸ | MEN1 | O00255 | 2/20 | 0.33 |
| ▸ | TSHR | P16473 | 1/20 | 0.33 |
| ▸ | TDP2 | O95551 | 1/20 | 0.32 |
| ▸ | GAA | P10253 | 1/20 | 0.32 |
| ▸ | MAPT | P10636 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5596277 | 0.80 | CYP3A4 (0.38) | CYP3A4HPGDALOX5PTGS1PTGS2 | |
| SCHEMBL5596374 | 0.79 | CA1 (0.42) | CYP3A4HPGDALOX5PTGS1PTGS2 | |
| SCHEMBL3047027 | 0.79 | CYP3A4 (0.56) | CYP3A4HPGDALOX5PTGS1PTGS2 | |
| SCHEMBL8908021 | 0.77 | CA2 (0.67) | CYP3A4HPGDPTGS1PTGS2CA1 | |
| SCHEMBL5596195 | 0.75 | ALDH1A1 (0.46) | ALOX5PTGS1PTGS2CA1CA2 | |
| SCHEMBL20620370 | 0.75 | CYP3A4 (0.37) | CYP3A4HPGDALOX5PTGS1PTGS2 | |
| SCHEMBL10106588 | 0.73 | CYP3A4 (0.62) | CYP3A4HPGDALOX5PTGS1PTGS2 | |
| SCHEMBL815911 | 0.71 | CYP3A4 (0.48) | CYP3A4HPGDALOX5PTGS1PTGS2 | |
| SCHEMBL11581623 | 0.71 | ABL1 (0.52) | CYP3A4HPGDALOX5PTGS1PTGS2 | |
| SCHEMBL22119888 | 0.69 | CYP3A4 (0.46) | CYP3A4HPGDALOX5PTGS1PTGS2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-7279537-B2 | Transition metal complexes and polymerization catalysts | SUMITOMO CHEMICAL COMPANY, LIMITED (JP) | 2007-10-09 | — | — | US | disclosed |
| US-20060229195-A1 | Transition metal complexes and polymerization catalysts | SUMITOMO CHEMICAL COMPANY, LIMITED (JP) | 2006-10-12 | — | — | US | disclosed |
| EP-1557423-A1 | TRANSITION METAL COMPLEXES AND POLYMERIZATION CATALYSTS | Sumitomo Chemical Company, Limited (JP) | 2005-07-27 | — | — | EP | disclosed |