SCHEMBL5596293

SCHEMBL5596293

CCP(c1cccc([Si](C)(C)C)c1O)c1cccc([Si](C)(C)C)c1O

nearest known ligand 0.33

Predicted protein targets (top 3)

geneUniProtsupporting neighboursconfidence
GABRA1 P14867 1/20 0.33
GABRB2 P47870 1/20 0.33
IDO1 P14902 1/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL5596215 0.86 GABRA1 (0.31) GABRA1GABRB2
SCHEMBL5596083 0.83 KCNH2 (0.33)
SCHEMBL5596003 0.80 KCNH2 (0.31)
SCHEMBL5596281 0.79 IDO1 (0.36) IDO1
SCHEMBL5596858 0.77 IDO1 (0.32) IDO1
SCHEMBL3119798 0.75 ALDH1A1 (0.41) GABRA1GABRB2IDO1
SCHEMBL5596048 0.75 ALDH1A1 (0.52) GABRA1GABRB2
SCHEMBL5596358 0.74 GABRA1 (0.33) GABRA1GABRB2IDO1
SCHEMBL5596214 0.74 CA2 (0.33) IDO1
SCHEMBL5596177 0.73 ESR1 (0.39)

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-7279537-B2 Transition metal complexes and polymerization catalysts SUMITOMO CHEMICAL COMPANY, LIMITED (JP) 2007-10-09 US disclosed
US-20060229195-A1 Transition metal complexes and polymerization catalysts SUMITOMO CHEMICAL COMPANY, LIMITED (JP) 2006-10-12 US disclosed
EP-1557423-A1 TRANSITION METAL COMPLEXES AND POLYMERIZATION CATALYSTS Sumitomo Chemical Company, Limited (JP) 2005-07-27 EP disclosed