SCHEMBL5596336

SCHEMBL5596336

Cc1cccc(P(Cc2ccccc2)c2cccc(C)c2O)c1O

nearest known ligand 0.45

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
ALDH1A1 P00352 3/20 0.45
TRPA1 O75762 1/20 0.41
KDM4E B2RXH2 1/20 0.39
HPGD P15428 1/20 0.39
HSD17B10 Q99714 1/20 0.39
KMT2A Q03164 2/20 0.38
CYP3A4 P08684 1/20 0.38
CYP2C9 P11712 1/20 0.38
MAOB P27338 1/20 0.37
SMN1; SMN2 Q16637 1/20 0.37
GPR52 Q9Y2T5 1/20 0.36
GABRA1 P14867 1/20 0.36
GABRB2 P47870 1/20 0.36
LMNA P02545 2/20 0.36
TAAR1 Q96RJ0 1/20 0.36
PTGER1 P34995 1/20 0.35
PTGER4 P35408 1/20 0.35
PTGER3 P43115 1/20 0.35
PTGER2 P43116 1/20 0.35
GAA P10253 1/20 0.34

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL7715002 0.83 TSHR (0.38) ALDH1A1KDM4EHPGDKMT2ASMN1; SMN2
SCHEMBL17529868 0.81 HTR7 (0.38) ALDH1A1TRPA1KMT2ACYP3A4CYP2C9
SCHEMBL5596432 0.79 GAA (0.40) ALDH1A1KDM4EKMT2ALMNAGAA
SCHEMBL5596003 0.78 KCNH2 (0.31)
SCHEMBL5596164 0.78 CA2 (0.50) ALDH1A1KMT2ACYP3A4CYP2C9GABRA1
SCHEMBL5596048 0.77 ALDH1A1 (0.52) ALDH1A1TRPA1KDM4EHPGDHSD17B10
SCHEMBL15657791 0.76 KMT2A (0.36) ALDH1A1TRPA1KMT2ACYP3A4CYP2C9
SCHEMBL5596855 0.75 AKR1B1 (0.39) ALDH1A1KDM4EHPGDHSD17B10CYP3A4
SCHEMBL5596343 0.74 MEN1 (0.38) ALDH1A1KDM4EHPGDHSD17B10KMT2A
SCHEMBL9016361 0.74 TSHR (0.33) ALDH1A1KDM4EHPGDKMT2ACYP3A4

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-7279537-B2 Transition metal complexes and polymerization catalysts SUMITOMO CHEMICAL COMPANY, LIMITED (JP) 2007-10-09 US disclosed
US-20060229195-A1 Transition metal complexes and polymerization catalysts SUMITOMO CHEMICAL COMPANY, LIMITED (JP) 2006-10-12 US disclosed
EP-1557423-A1 TRANSITION METAL COMPLEXES AND POLYMERIZATION CATALYSTS Sumitomo Chemical Company, Limited (JP) 2005-07-27 EP disclosed