Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CA1 | P00915 | 1/20 | 0.42 |
| ▸ | CA2 | P00918 | 1/20 | 0.42 |
| ▸ | MEN1 | O00255 | 2/20 | 0.39 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.39 |
| ▸ | TSHR | P16473 | 1/20 | 0.39 |
| ▸ | PDE4A | P27815 | 1/20 | 0.37 |
| ▸ | PDE4B | Q07343 | 1/20 | 0.37 |
| ▸ | PDE4C | Q08493 | 1/20 | 0.37 |
| ▸ | PDE4D | Q08499 | 1/20 | 0.37 |
| ▸ | CYP3A4 | P08684 | 4/20 | 0.36 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.36 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.36 |
| ▸ | TP53 | P04637 | 2/20 | 0.36 |
| ▸ | MAPT | P10636 | 2/20 | 0.36 |
| ▸ | HPGD | P15428 | 2/20 | 0.36 |
| ▸ | ALOX5 | P09917 | 2/20 | 0.36 |
| ▸ | PTGS1 | P23219 | 2/20 | 0.36 |
| ▸ | PTGS2 | P35354 | 2/20 | 0.36 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.36 |
| ▸ | USP2 | O75604 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5596439 | 0.81 | ESR1 (0.39) | CA2MEN1KMT2ASMN1; SMN2ALDH1A1 | |
| SCHEMBL5596282 | 0.77 | CA2 (0.55) | CA1CA2KMT2ACYP3A4SMN1; SMN2 | |
| SCHEMBL5596345 | 0.74 | GABRA1 (0.55) | CA2MEN1KMT2ATSHRCYP3A4 | |
| SCHEMBL10954074 | 0.73 | CA2 (0.77) | CA1CA2MEN1KMT2ACYP3A4 | |
| SCHEMBL5596094 | 0.71 | NPC1 (0.41) | CYP3A4HPGDPTGS1PTGS2ESR1 | |
| SCHEMBL3047027 | 0.70 | CYP3A4 (0.56) | CA1CA2MEN1KMT2ATSHR | |
| SCHEMBL5596856 | 0.69 | ESR1 (0.43) | MEN1KMT2ATSHRALDH1A1TP53 | |
| SCHEMBL31612024 | 0.69 | CA4 (0.54) | CA1CA2ALDH1A1CA4 | |
| SCHEMBL10951167 | 0.68 | CA1 (0.52) | CA1CA2MEN1KMT2ACYP3A4 | |
| SCHEMBL16900546 | 0.68 | ALDH1A1 (0.48) | MEN1KMT2APDE4APDE4DCYP3A4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-7279537-B2 | Transition metal complexes and polymerization catalysts | SUMITOMO CHEMICAL COMPANY, LIMITED (JP) | 2007-10-09 | — | — | US | disclosed |
| US-20060229195-A1 | Transition metal complexes and polymerization catalysts | SUMITOMO CHEMICAL COMPANY, LIMITED (JP) | 2006-10-12 | — | — | US | disclosed |
| EP-1557423-A1 | TRANSITION METAL COMPLEXES AND POLYMERIZATION CATALYSTS | Sumitomo Chemical Company, Limited (JP) | 2005-07-27 | — | — | EP | disclosed |