Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MEN1 | O00255 | 3/20 | 0.38 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.38 |
| ▸ | TSHR | P16473 | 2/20 | 0.38 |
| ▸ | CYP3A4 | P08684 | 5/20 | 0.35 |
| ▸ | MAPT | P10636 | 5/20 | 0.35 |
| ▸ | SMN1; SMN2 | Q16637 | 4/20 | 0.35 |
| ▸ | TP53 | P04637 | 3/20 | 0.35 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.35 |
| ▸ | ALOX5 | P09917 | 3/20 | 0.35 |
| ▸ | PTGS1 | P23219 | 3/20 | 0.35 |
| ▸ | PTGS2 | P35354 | 3/20 | 0.35 |
| ▸ | HPGD | P15428 | 2/20 | 0.35 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.35 |
| ▸ | USP2 | O75604 | 1/20 | 0.35 |
| ▸ | TRPV1 | Q8NER1 | 1/20 | 0.35 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.35 |
| ▸ | GAA | P10253 | 3/20 | 0.34 |
| ▸ | BACE1 | P56817 | 1/20 | 0.34 |
| ▸ | ABCG2 | Q9UNQ0 | 2/20 | 0.34 |
| ▸ | CA4 | P22748 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5596223 | 0.89 | MEN1 (0.38) | MEN1KMT2ATSHRCYP3A4MAPT | |
| SCHEMBL5596075 | 0.82 | ALDH1A1 (0.39) | MEN1KMT2AMAPTALDH1A1ALOX5 | |
| SCHEMBL5595890 | 0.80 | CYP3A4 (0.39) | KMT2ACYP3A4MAPTSMN1; SMN2ALDH1A1 | |
| SCHEMBL5596039 | 0.76 | MEN1 (0.41) | MEN1KMT2ATSHRCYP3A4MAPT | |
| SCHEMBL5596527 | 0.75 | ALDH1A1 (0.43) | KMT2ATSHRCYP3A4MAPTALDH1A1 | |
| SCHEMBL5596535 | 0.73 | NPC1 (0.39) | MEN1KMT2ATSHRCYP3A4MAPT | |
| SCHEMBL5596343 | 0.72 | MEN1 (0.38) | MEN1KMT2ATSHRCYP3A4MAPT | |
| SCHEMBL5596170 | 0.71 | CYP3A4 (0.43) | MEN1KMT2ATSHRCYP3A4MAPT | |
| SCHEMBL5596225 | 0.70 | MEN1 (0.37) | MEN1KMT2ATSHRCYP3A4MAPT | |
| SCHEMBL5596245 | 0.70 | LMNA (0.39) | MEN1KMT2AMAPTALDH1A1ALOX5 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-7279537-B2 | Transition metal complexes and polymerization catalysts | SUMITOMO CHEMICAL COMPANY, LIMITED (JP) | 2007-10-09 | — | — | US | disclosed |
| US-20060229195-A1 | Transition metal complexes and polymerization catalysts | SUMITOMO CHEMICAL COMPANY, LIMITED (JP) | 2006-10-12 | — | — | US | disclosed |
| EP-1557423-A1 | TRANSITION METAL COMPLEXES AND POLYMERIZATION CATALYSTS | Sumitomo Chemical Company, Limited (JP) | 2005-07-27 | — | — | EP | disclosed |