Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LMNA | P02545 | 4/20 | 0.39 |
| ▸ | GAA | P10253 | 4/20 | 0.39 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.39 |
| ▸ | MAPT | P10636 | 2/20 | 0.39 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.39 |
| ▸ | PTGS1 | P23219 | 3/20 | 0.35 |
| ▸ | PTGS2 | P35354 | 3/20 | 0.35 |
| ▸ | TTR | P02766 | 1/20 | 0.35 |
| ▸ | ALOX5 | P09917 | 1/20 | 0.35 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.35 |
| ▸ | ESR1 | P03372 | 1/20 | 0.34 |
| ▸ | ESR2 | Q92731 | 1/20 | 0.34 |
| ▸ | HTT | P42858 | 1/20 | 0.33 |
| ▸ | PKM | P14618 | 1/20 | 0.32 |
| ▸ | MEN1 | O00255 | 1/20 | 0.32 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.32 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.32 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.31 |
| ▸ | CYP2A6 | P11509 | 1/20 | 0.31 |
| ▸ | ADORA2A | P29274 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5596075 | 0.87 | ALDH1A1 (0.39) | LMNAGAAALDH1A1MAPTKDM4E | |
| SCHEMBL5596223 | 0.82 | MEN1 (0.38) | GAAALDH1A1MAPTKDM4EPTGS1 | |
| SCHEMBL5596458 | 0.81 | NPC1 (0.39) | LMNAALDH1A1MAPTKDM4EPTGS1 | |
| SCHEMBL5596608 | 0.80 | ALDH1A1 (0.43) | GAAALDH1A1MAPTKDM4EPTGS1 | |
| SCHEMBL5595996 | 0.79 | TRPA1 (0.39) | LMNAGAAALDH1A1MAPTL3MBTL1 | |
| SCHEMBL5596396 | 0.78 | ALDH1A1 (0.34) | LMNAGAAALDH1A1MAPTKDM4E | |
| SCHEMBL5596151 | 0.77 | ALDH1A1 (0.48) | LMNAGAAALDH1A1MAPTKDM4E | |
| SCHEMBL5595970 | 0.73 | GABRA1 (0.40) | LMNAGAAALDH1A1MAPTTTR | |
| SCHEMBL5596432 | 0.72 | GAA (0.40) | LMNAGAAALDH1A1MAPTKDM4E | |
| SCHEMBL5596474 | 0.72 | ESR1 (0.41) | LMNAALDH1A1MAPTKDM4EL3MBTL1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-7279537-B2 | Transition metal complexes and polymerization catalysts | SUMITOMO CHEMICAL COMPANY, LIMITED (JP) | 2007-10-09 | — | — | US | disclosed |
| US-20060229195-A1 | Transition metal complexes and polymerization catalysts | SUMITOMO CHEMICAL COMPANY, LIMITED (JP) | 2006-10-12 | — | — | US | disclosed |
| EP-1557423-A1 | TRANSITION METAL COMPLEXES AND POLYMERIZATION CATALYSTS | Sumitomo Chemical Company, Limited (JP) | 2005-07-27 | — | — | EP | disclosed |