Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM1A | O60341 | 1/20 | 0.41 |
| ▸ | HTR1A | P08908 | 6/20 | 0.39 |
| ▸ | DRD2 | P14416 | 3/20 | 0.38 |
| ▸ | HTR2A | P28223 | 3/20 | 0.38 |
| ▸ | DRD3 | P35462 | 3/20 | 0.38 |
| ▸ | DRD1 | P21728 | 2/20 | 0.38 |
| ▸ | DRD5 | P21918 | 1/20 | 0.38 |
| ▸ | DRD4 | P21917 | 2/20 | 0.38 |
| ▸ | ADRA2C | P18825 | 1/20 | 0.38 |
| ▸ | HTR2C | P28335 | 1/20 | 0.38 |
| ▸ | HRH1 | P35367 | 1/20 | 0.38 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.37 |
| ▸ | HTT | P42858 | 1/20 | 0.37 |
| ▸ | MEN1 | O00255 | 1/20 | 0.37 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1110443 | 0.87 | POLB (0.41) | KDM4EHTTKMT2A | |
| SCHEMBL5596259 | 0.80 | LMNA (0.50) | KDM4EHTTMEN1KMT2A | |
| SCHEMBL6293414 | 0.80 | CHRNA7 (0.40) | KDM4EMEN1KMT2A | |
| SCHEMBL5597094 | 0.77 | HTR3A (0.42) | MEN1KMT2A | |
| SCHEMBL5801843 | 0.75 | CYP1A2 (0.43) | DRD1DRD5DRD4KDM4E | |
| SCHEMBL3513447 | 0.75 | KDM4E (0.36) | HRH1KDM4EHTTMEN1KMT2A | |
| SCHEMBL1750786 | 0.74 | MKNK1 (0.49) | KDM4EHTTMEN1KMT2A | |
| SCHEMBL2322094 | 0.73 | CCNT1 (0.35) | KDM4EHTTMEN1KMT2A | |
| SCHEMBL5801122 | 0.73 | MAPT (0.66) | HTTKMT2A | |
| SCHEMBL6033433 | 0.73 | CXCR4 (0.45) | KDM4EHTTMEN1KMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1696909-B1 | BENZOTHIAZOLE DERIVATIVES FOR THE TREATMENT OF DIABETES | SERONO LAB (CH) | 2007-11-14 | — | — | EP | claimed |