Predicted protein targets (top 3)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CYP3A4 | P08684 | 1/20 | 0.33 |
| ▸ | SLC7A5 | Q01650 | 1/20 | 0.33 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Histidine SCHEMBL28595604 | 0.85 | SLC7A5 (0.45) | CYP3A4SLC7A5CYP1A2 | |
| Histidine SCHEMBL2551674 | 0.85 | SLC7A5 (0.45) | CYP3A4SLC7A5CYP1A2 | |
| Histidine SCHEMBL388561 | 0.84 | SLC7A5 (0.47) | CYP3A4SLC7A5CYP1A2 | |
| Histidine SCHEMBL3258 | 0.84 | SLC7A5 (0.47) | CYP3A4SLC7A5CYP1A2 | |
| SCHEMBL358921 | 0.84 | SCN10A (0.35) | CYP3A4SLC7A5CYP1A2 | |
| Histidine SCHEMBL3259 | 0.84 | SLC7A5 (0.47) | CYP3A4SLC7A5CYP1A2 | |
| Histidine SCHEMBL995910 | 0.84 | SLC7A5 (0.47) | CYP3A4SLC7A5CYP1A2 | |
| Histidine SCHEMBL18824897 | 0.84 | SLC7A5 (0.47) | CYP3A4SLC7A5CYP1A2 | |
| Histidine SCHEMBL163443 | 0.84 | SLC7A5 (0.47) | CYP3A4SLC7A5CYP1A2 | |
| Histidine SCHEMBL8080341 | 0.84 | SLC7A5 (0.47) | CYP3A4SLC7A5CYP1A2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1197222-B1 | A stabilized pharmaceutical formulation comprising growth hormone and histidine | NOVO NORDISK AS (DK) | 2007-08-01 | — | — | EP | disclosed |
| US-6187928-B1 | TREATING FUNGAL DISEASES | THE ROCKEFELLER UNIVERSITY | 2001-02-13 | — | — | US | disclosed |
| US-5849700-A | Pharmaceutical formulation | NOVO NORDISK A/S (DK) | 1998-12-15 | — | — | US | disclosed |