Predicted protein targets (top 7)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.36 |
| ▸ | CA2 | P00918 | 2/20 | 0.36 |
| ▸ | HCRTR2 | O43614 | 10/20 | 0.34 |
| ▸ | HCRTR1 | O43613 | 8/20 | 0.34 |
| ▸ | TMEM97 | Q5BJF2 | 2/20 | 0.33 |
| ▸ | SIGMAR1 | Q99720 | 2/20 | 0.33 |
| ▸ | TBXA2R | P21731 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL15151257 | 0.85 | TSHR (0.41) | L3MBTL1CA2HCRTR2HCRTR1TMEM97 | |
| SCHEMBL28912789 | 0.85 | CA2 (0.37) | L3MBTL1CA2HCRTR2HCRTR1 | |
| SCHEMBL10374683 | 0.84 | HSD17B1 (0.39) | L3MBTL1HCRTR2HCRTR1TMEM97SIGMAR1 | |
| SCHEMBL10374015 | 0.82 | CA2 (0.35) | L3MBTL1CA2HCRTR2HCRTR1TMEM97 | |
| SCHEMBL10965421 | 0.80 | L3MBTL1 (0.37) | L3MBTL1CA2HCRTR2HCRTR1 | |
| SCHEMBL24082907 | 0.79 | CA2 (0.37) | L3MBTL1CA2HCRTR2HCRTR1TMEM97 | |
| SCHEMBL3683016 | 0.79 | MAPT (0.33) | L3MBTL1CA2 | |
| SCHEMBL14700449 | 0.79 | CA2 (0.33) | L3MBTL1CA2 | |
| SCHEMBL22309795 | 0.77 | CA2 (0.33) | L3MBTL1CA2 | |
| SCHEMBL29086833 | 0.76 | L3MBTL1 (0.33) | L3MBTL1CA2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1760083-B1 | Rapamycin hydroxyesters, process for their preparation and pharmaceutical compositions containing them | WYETH LLC (US) | 2011-12-14 | — | — | EP | claimed |
| EP-1266899-B1 | Rapamycin hdroxyesters, process for their preparation and pharmaceutical compositions containing them | WYETH CORP (US) | 2007-01-03 | — | — | EP | claimed |
| CN-112770778-A | External preparation containing non-lamellar liquid crystal forming lipid | 法纳克斯株式会社 | 2021-05-07 | — | — | CN | disclosed |
| EP-0189586-B1 | PROCESS FOR THE PREPARATION OF SALTS OF 1,3-DIOXOLANE-4-CARBOXYLIC ACIDS | Henkel Kommanditgesellschaft auf Aktien (DE) | 1989-05-24 | — | — | EP | disclosed |
| EP-0189586-A1 | Process for the preparation of salts of 1,3-dioxolane-4-carboxylic acids | Henkel Kommanditgesellschaft auf Aktien (DE) | 1986-08-06 | — | — | EP | disclosed |