Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PLK1 | P53350 | 1/20 | 0.37 |
| ▸ | MEN1 | O00255 | 2/20 | 0.36 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.36 |
| ▸ | HTT | P42858 | 2/20 | 0.36 |
| ▸ | PPARG | P37231 | 2/20 | 0.35 |
| ▸ | PPARA | Q07869 | 2/20 | 0.35 |
| ▸ | RHEB | Q15382 | 1/20 | 0.35 |
| ▸ | ATM | Q13315 | 1/20 | 0.35 |
| ▸ | F2RL1 | P55085 | 2/20 | 0.33 |
| ▸ | LMNA | P02545 | 1/20 | 0.33 |
| ▸ | MAPT | P10636 | 1/20 | 0.33 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.33 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.33 |
| ▸ | CA1 | P00915 | 1/20 | 0.33 |
| ▸ | CA2 | P00918 | 1/20 | 0.33 |
| ▸ | MMP2 | P08253 | 1/20 | 0.33 |
| ▸ | CA9 | Q16790 | 1/20 | 0.33 |
| ▸ | TACR2 | P21452 | 1/20 | 0.33 |
| ▸ | GCGR | P47871 | 1/20 | 0.32 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7206819 | 0.83 | XDH (0.35) | PLK1MEN1KMT2AHTTPPARG | |
| SCHEMBL4642034 | 0.82 | PPARG (0.33) | MEN1KMT2AHTTPPARGPPARA | |
| SCHEMBL9791533 | 0.80 | PLK1 (0.42) | PLK1MEN1KMT2AHTTPPARG | |
| SCHEMBL9791462 | 0.80 | PLK1 (0.42) | PLK1MEN1KMT2AHTTPPARG | |
| SCHEMBL5597307 | 0.79 | PPARG (0.33) | PPARGPPARAF2RL1MAPTCA1 | |
| SCHEMBL2353622 | 0.73 | CYP17A1 (0.43) | PLK1MEN1KMT2AHTTLMNA | |
| SCHEMBL19642925 | 0.70 | CYP1A2 (0.44) | F2RL1SMN1; SMN2MMP2CYP3A4CYP2C9 | |
| SCHEMBL9791518 | 0.69 | PTGDR2 (0.46) | PLK1MEN1KMT2AHTTRHEB | |
| SCHEMBL5597451 | 0.67 | HTT (0.39) | PLK1MEN1KMT2AHTTRHEB | |
| SCHEMBL9791516 | 0.66 | ALDH1A1 (0.41) | PLK1HTTATMSMN1; SMN2L3MBTL1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1804819-A4 | USE OF AROMATASE INHIBITORS FOR ENDOMETRIAL THINNING IN PREPARATION FOR SURGICAL PROCEDURES ON THE ENDOMETRIAL CAVITY AND UTERUS | UNIV WAYNE STATE (US) | 2007-12-12 | — | — | EP | disclosed |
| EP-1804819-A2 | USE OF AROMATASE INHIBITORS FOR ENDOMETRIAL THINNING IN PREPARATION FOR SURGICAL PROCEDURES ON THE ENDOMETRIAL CAVITY AND UTERUS | WAYNE STATE UNIVERSITY (US) | 2007-07-11 | — | — | EP | disclosed |
| WO-2006041939-A2 | USE OF AROMATASE INHIBITORS FOR ENDOMETRIAL THINNING IN PREPARATION FOR SURGICAL PROCEDURES ON THE ENDOMETRIAL CAVITY AND UTERUS | WAYNE STATE UNIVERSITY (US) | 2006-04-20 | — | — | WO | disclosed |