Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | XDH | P47989 | 3/20 | 0.35 |
| ▸ | NPC1 | O15118 | 1/20 | 0.35 |
| ▸ | RAB9A | P51151 | 1/20 | 0.35 |
| ▸ | MEN1 | O00255 | 1/20 | 0.34 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.34 |
| ▸ | ATM | Q13315 | 1/20 | 0.34 |
| ▸ | BCAT2 | O15382 | 1/20 | 0.33 |
| ▸ | MAPT | P10636 | 2/20 | 0.33 |
| ▸ | HTT | P42858 | 2/20 | 0.33 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.33 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.33 |
| ▸ | PPARG | P37231 | 2/20 | 0.32 |
| ▸ | PPARA | Q07869 | 2/20 | 0.32 |
| ▸ | LMNA | P02545 | 1/20 | 0.32 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.32 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.32 |
| ▸ | PLK1 | P53350 | 1/20 | 0.32 |
| ▸ | SGMS2 | Q8NHU3 | 1/20 | 0.32 |
| ▸ | TACR2 | P21452 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5597450 | 0.83 | PLK1 (0.37) | MEN1KMT2AATMMAPTHTT | |
| SCHEMBL5597307 | 0.80 | PPARG (0.33) | XDHNPC1RAB9ABCAT2MAPT | |
| SCHEMBL4642034 | 0.76 | PPARG (0.33) | NPC1RAB9AMEN1KMT2AATM | |
| SCHEMBL2356498 | 0.76 | CYP17A1 (0.39) | NPC1RAB9AMEN1KMT2AKDM4E | |
| SCHEMBL4642066 | 0.71 | CCR5 (0.39) | XDHMAPTNPSR1 | |
| SCHEMBL7206821 | 0.71 | NAMPT (0.36) | XDHNPC1RAB9AMAPTHTT | |
| SCHEMBL5597175 | 0.69 | FPR2 (0.38) | XDHNPC1RAB9AMAPTHTT | |
| SCHEMBL4642508 | 0.69 | MRGPRX4 (0.39) | MEN1KMT2AMAPTHTTKDM4E | |
| SCHEMBL5597418 | 0.67 | MRGPRX4 (0.36) | MEN1KMT2AMAPTKDM4ELMNA | |
| SCHEMBL19642925 | 0.66 | CYP1A2 (0.44) | SMN1; SMN2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2003082299-A1 | IMPROVED HORMONE REPLACEMENT THERAPY | JENCAP RESEARCH LTD. (CA) | 2003-10-09 | — | — | WO | disclosed |