Predicted protein targets (top 4)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CALCA | P06881 | 2/20 | 0.47 |
| ▸ | CALCRL | Q16602 | 18/20 | 0.46 |
| ▸ | CYP3A4 | P08684 | 14/20 | 0.46 |
| ▸ | RAMP1 | O60894 | 2/20 | 0.44 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6270466 | 0.75 | CALCA (0.61) | CALCACALCRLCYP3A4RAMP1 | |
| SCHEMBL3876511 | 0.75 | CALCA (0.71) | CALCACALCRLCYP3A4RAMP1 | |
| SCHEMBL4586249 | 0.75 | CALCRL (0.59) | CALCACALCRLCYP3A4RAMP1 | |
| SCHEMBL4717830 | 0.75 | CALCRL (0.49) | CALCACALCRLCYP3A4RAMP1 | |
| SCHEMBL3965813 | 0.75 | CALCRL (0.64) | CALCACALCRLCYP3A4RAMP1 | |
| SCHEMBL3960011 | 0.74 | CALCRL (0.66) | CALCRLCYP3A4 | |
| SCHEMBL3959637 | 0.73 | CALCRL (0.67) | CALCRLCYP3A4 | |
| SCHEMBL4585961 | 0.73 | CALCRL (0.47) | CALCACALCRLCYP3A4 | |
| SCHEMBL6272723 | 0.73 | CALCA (0.63) | CALCACALCRLCYP3A4RAMP1 | |
| SCHEMBL6267999 | 0.73 | CALCA (0.63) | CALCACALCRLCYP3A4RAMP1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1833478-A1 | USE OF SELECTED CGRP ANTAGONISTS IN COMBINATION WITH OTHER ANTIMIGRAINE MEDICAL SUBSTANCES FOR THE TREATMENT OF MIGRAINE | Boehringer Ingelheim International GmbH (DE) | 2007-09-19 | — | — | EP | claimed |
| WO-2006072413-A1 | USE OF SELECTED CGRP ANTAGONISTS IN COMBINATION WITH OTHER ANTIMIGRAINE MEDICAL SUBSTANCES FOR THE TREATMENT OF MIGRAINE | BOEHRINGER INGELHEIM INTERNATIONAL GMBH (DE) | 2006-07-13 | — | — | WO | claimed |